Development of a Convenient and Quantitative Method for Evaluating Photosensitizing Activity Using Thiazolyl Blue Formazan Dye.

Smee Kang, Yeong Ji Oh, Mi-Ri Kim, Yu Na Jung, Eiseul Song, Hyowon Lee, Jungil Hong

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Photodegradation of Turmeric Oleoresin Under Fluorescent Light and White LED: Impacts on the Chemical Stability, Bioactivity, and Photosensitizing Property of Curcuminoids.Molecules (Basel, Switzerland) · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Smee KangDepartment of Food Science and Technology, College of Science and Convergence Technology, Seoul Women's University, 621, Hwarangro, Nowon-gu, Seoul 01797, Republic of Korea.

Yeong Ji OhMajor in Food Science & Biotechnology, Institute of Bio Engineering, College of Future Convergence, Eulji University, Seongnam 13135, Republic of Korea.ORCID 0000-0003-4014-9849

Mi-Ri KimDepartment of Food Science and Technology, College of Science and Convergence Technology, Seoul Women's University, 621, Hwarangro, Nowon-gu, Seoul 01797, Republic of Korea.

Yu Na JungDepartment of Food Science and Technology, College of Science and Convergence Technology, Seoul Women's University, 621, Hwarangro, Nowon-gu, Seoul 01797, Republic of Korea.

Eiseul SongDepartment of Food Science and Technology, College of Science and Convergence Technology, Seoul Women's University, 621, Hwarangro, Nowon-gu, Seoul 01797, Republic of Korea.

Hyowon LeeDepartment of Food Science and Technology, College of Science and Convergence Technology, Seoul Women's University, 621, Hwarangro, Nowon-gu, Seoul 01797, Republic of Korea.

Jungil HongDepartment of Food Science and Technology, College of Science and Convergence Technology, Seoul Women's University, 621, Hwarangro, Nowon-gu, Seoul 01797, Republic of Korea.ORCID 0000-0002-3878-6059

Funding

National Research Foundation of Korea 2016R1A2B1007540, 2019R1A2C1089617, and 2021R1F1A1051466

6 · The paper itself

Abstract

Photosensitizers cause oxidative damages in various biological systems under light. In this study, the method for analyzing photosensitizing activity of various dietary and medicinal sources was developed using 1-(4,5-dimethylthiazol-2-yl)-3,5-diphenylformazan (thiazolyl blue formazan; MTT-F) as a probe. Significant and quantitative decolorization of MTT-F was observed in the presence of photosensitizers used in this study under light but not under dark conditions. The decolorization of MTT-F occurred irradiation time-, light intensity-, and photosensitizer concentration-dependently. The decolorized MTT-F was reversibly reduced by living cells; the LC-MS/MS results indicated the formation of oxidized products with -1

Indexed as

FormazansPhotosensitizing AgentsTetrazolium SaltsChromatography, LiquidColoring AgentsHumansLightTandem Mass SpectrometryThiazolesColoring AgentsFormazansPhotosensitizing AgentsTetrazolium SaltsThiazolesthiazolyl blueMTTMTT formazanphotosensitizerphotosensitizing activityquantitative analysis

Identifiers

PMID38893346

DOI10.3390/molecules29112471

PMCPMC11173384

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.