Evidence map›Paper›PMID 38893275›Full record

ArticleCancers2024

Incidence and Relative Survival of Patients with Merkel Cell Carcinoma in North Rhine-Westphalia, Germany, 2008-2021.

Andreas Stang, Lennart Möller, Ina Wellmann, Kevin Claaßen, Hiltraud Kajüter, Selma Ugurel, Jürgen C Becker

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Radiotherapy for Merkel cell carcinoma: recommendations from the DEGRO Dermatooncology Working Group.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andreas StangInstitute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany.ORCID 0000-0001-6363-9061
Lennart MöllerCancer Registry of North Rhine-Westphalia, Gesundheitscampus 10, 44801 Bochum, Germany.ORCID 0000-0003-1090-9595
Ina WellmannCancer Registry of North Rhine-Westphalia, Gesundheitscampus 10, 44801 Bochum, Germany.ORCID 0009-0001-1831-2542
Kevin ClaaßenCancer Registry of North Rhine-Westphalia, Gesundheitscampus 10, 44801 Bochum, Germany.ORCID 0000-0002-5375-2869
Hiltraud KajüterCancer Registry of North Rhine-Westphalia, Gesundheitscampus 10, 44801 Bochum, Germany.ORCID 0000-0003-3729-4447
Selma UgurelDepartment of Dermatology, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany.ORCID 0000-0002-9384-6704
Jürgen C BeckerDepartment of Dermatology, University Hospital Essen, Hufelandstr. 55, 45147 Essen, Germany.ORCID 0000-0001-9183-653X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo date, only a few population-representative studies have been carried out on the rare Merkel cell carcinoma (MCC). We provide incidence and survival estimates of MCC, including the conditional relative survival.

methodsWe analyzed data from the cancer registry of North Rhine-Westphalia, Germany, 2008-2021, covering a population of 18 million. We included all newly diagnosed MCCs and calculated age-standardized (old European Standard population) incidence rates and unconditional and conditional relative survival.

resultsOur analysis included 2164 MCC patients. The age-standardized incidence of MCC was 5.2 (men) and 3.8 (women) per million person-years. The 5-year relative survival was 58.8% (men) and 70.7% (women). Survival was lower among men than women in all age-sex groups and was highest for MCC of the upper extremity in both men (68.2%) and women (79.3%). The sex difference in survival is particularly due to the better survival of women with MCC of the head and neck. In terms of survival, the first two years are particularly critical.

conclusionsOur data validate the worse survival among men and highlights a more favorable prognosis for MCCs located on the limbs. The first two years after diagnosis of MCC are the years with the highest excess mortality.

Indexed as

GermanyincidenceMerkel cell(MeSH) carcinomaregistriessurvival analysis

Identifiers

PMID38893275
PMCPMC11171844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.