Evidence map›Paper›PMID 38893102›Full record

ReviewCancers2024

Early Breast Cancer Risk Assessment: Integrating Histopathology with Artificial Intelligence.

Mariia Ivanova, Carlo Pescia, Dario Trapani, Konstantinos Venetis, Chiara Frascarelli, Eltjona Mane, Giulia Cursano, Elham Sajjadi, Cristian Scatena, Bruna Cerbelli and 6 more

Abstract readReview
In one paragraph

Review in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. AI in Prostate Cancer Screening & Diagnosis: A Registry-Based Study of ClinicalTrials.gov Trials.Inquiry : a journal of medical care organization, provision and financing
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Mariia IvanovaDivision of Pathology, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-7636-1000
Carlo PesciaDivision of Pathology, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0003-0657-506X
Dario TrapaniDivision of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Konstantinos VenetisDivision of Pathology, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Chiara FrascarelliDivision of Pathology, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Eltjona ManeDivision of Pathology, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0009-0000-8609-7584
Giulia CursanoDivision of Pathology, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Elham SajjadiDivision of Pathology, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0001-7401-1843
Cristian ScatenaDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-4862-0845
Bruna CerbelliDepartment of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 00185 Rome, Italy.
Giulia d'AmatiDepartment of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-6959-691X
Francesca Maria PortaDivision of Pathology, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0003-2841-5024
Elena Guerini-RoccoDivision of Pathology, European Institute of Oncology IRCCS, 20141 Milan, Italy.
Carmen CriscitielloDivision of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0001-9064-0113
Giuseppe CuriglianoDivision of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0003-1781-2518
Nicola FuscoDivision of Pathology, European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0002-9101-9131

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Effective risk assessment in early breast cancer is essential for informed clinical decision-making, yet consensus on defining risk categories remains challenging. This paper explores evolving approaches in risk stratification, encompassing histopathological, immunohistochemical, and molecular biomarkers alongside cutting-edge artificial intelligence (AI) techniques. Leveraging machine learning, deep learning, and convolutional neural networks, AI is reshaping predictive algorithms for recurrence risk, thereby revolutionizing diagnostic accuracy and treatment planning. Beyond detection, AI applications extend to histological subtyping, grading, lymph node assessment, and molecular feature identification, fostering personalized therapy decisions. With rising cancer rates, it is crucial to implement AI to accelerate breakthroughs in clinical practice, benefiting both patients and healthcare providers. However, it is important to recognize that while AI offers powerful automation and analysis tools, it lacks the nuanced understanding, clinical context, and ethical considerations inherent to human pathologists in patient care. Hence, the successful integration of AI into clinical practice demands collaborative efforts between medical experts and computational pathologists to optimize patient outcomes.

Indexed as

artificial intelligencebiomarkersbreast cancerdeep learningearly breast cancerpathologypredictive algorithmsrisk stratification

Identifiers

PMID38893102
PMCPMC11171409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.