Evidence map›Paper›PMID 38893086›Full record

ArticleCancers2024

Different Patterns of Care and Survival Outcomes in Transplant-Centre Managed Patients with Early-Stage HCC: Real-World Data from an Australian Multi-Centre Cohort Study.

Jonathan Abdelmalak, Simone I Strasser, Natalie L Ngu, Claude Dennis, Marie Sinclair, Avik Majumdar, Kate Collins, Katherine Bateman, Anouk Dev, Joshua H Abasszade and 25 more

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Jonathan AbdelmalakDepartment of Gastroenterology, Alfred Health, Melbourne, VIC 3004, Australia.ORCID 0000-0001-7550-8202
Simone I StrasserAW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia.ORCID 0000-0001-6374-1525
Natalie L NguAW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia.
Claude DennisAW Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Camperdown, NSW 2050, Australia.
Marie SinclairDepartment of Gastroenterology, Austin Hospital, Heidelberg, VIC 3084, Australia.ORCID 0000-0003-0657-3048
Avik MajumdarDepartment of Gastroenterology, Austin Hospital, Heidelberg, VIC 3084, Australia.
Kate CollinsDepartment of Gastroenterology, Austin Hospital, Heidelberg, VIC 3084, Australia.ORCID 0000-0001-6357-3867
Katherine BatemanDepartment of Gastroenterology, Austin Hospital, Heidelberg, VIC 3084, Australia.
Anouk DevDepartment of Gastroenterology, Monash Health, Clayton, VIC 3168, Australia.
Joshua H AbasszadeDepartment of Gastroenterology, Monash Health, Clayton, VIC 3168, Australia.ORCID 0000-0001-5469-4317
Zina ValaydonDepartment of Gastroenterology, Western Health, Footscray, VIC 3011, Australia.
Daniel SaittaDepartment of Gastroenterology, Western Health, Footscray, VIC 3011, Australia.
Kathryn GazelakisDepartment of Gastroenterology, Western Health, Footscray, VIC 3011, Australia.
Susan ByersDepartment of Gastroenterology, Western Health, Footscray, VIC 3011, Australia.
Jacinta HolmesDepartment of Gastroenterology, St Vincent's Hospital Melbourne, Fitzroy, VIC 3065, Australia.
Alexander J ThompsonDepartment of Gastroenterology, St Vincent's Hospital Melbourne, Fitzroy, VIC 3065, Australia.
Dhivya PandiarajaDepartment of Gastroenterology, St Vincent's Hospital Melbourne, Fitzroy, VIC 3065, Australia.
Steven BollipoDepartment of Gastroenterology, John Hunter Hospital, New Lambton Heights, NSW 2305, Australia.
Suresh SharmaDepartment of Gastroenterology, John Hunter Hospital, New Lambton Heights, NSW 2305, Australia.ORCID 0000-0003-4785-3337
Merlyn JosephDepartment of Gastroenterology, John Hunter Hospital, New Lambton Heights, NSW 2305, Australia.
Rohit SawhneyDepartment of Gastroenterology, Eastern Health, Box Hill, VIC 3128, Australia.ORCID 0000-0002-8131-2182
Amanda NicollDepartment of Gastroenterology, Eastern Health, Box Hill, VIC 3128, Australia.ORCID 0000-0002-1855-2757
Nicholas BattDepartment of Gastroenterology, Eastern Health, Box Hill, VIC 3128, Australia.
Myo J TangDepartment of Gastroenterology, Alfred Health, Melbourne, VIC 3004, Australia.
Stephen RiordanDepartment of Gastroenterology, Prince of Wales Hospital, Randwick, NSW 2031, Australia.
Nicholas HannahDepartment of Gastroenterology, Royal Melbourne Hospital, Parkville, VIC 3052, Australia.
James HaridyDepartment of Gastroenterology, Royal Melbourne Hospital, Parkville, VIC 3052, Australia.ORCID 0000-0002-1534-3466
Siddharth SoodDepartment of Gastroenterology, Royal Melbourne Hospital, Parkville, VIC 3052, Australia.
Eileen LamDepartment of Medicine, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia.ORCID 0000-0002-1244-3322
Elysia GreenhillDepartment of Medicine, Central Clinical School, Monash University, Melbourne, VIC 3004, Australia.
John LubelDepartment of Gastroenterology, Alfred Health, Melbourne, VIC 3004, Australia.
William KempDepartment of Gastroenterology, Alfred Health, Melbourne, VIC 3004, Australia.ORCID 0000-0002-0787-7273
Ammar MajeedDepartment of Gastroenterology, Alfred Health, Melbourne, VIC 3004, Australia.
John ZalcbergSchool of Public Health and Preventative Medicine, Monash University, Melbourne, VIC 3004, Australia.ORCID 0000-0002-6624-0782
Stuart K RobertsDepartment of Gastroenterology, Alfred Health, Melbourne, VIC 3004, Australia.ORCID 0000-0002-9015-7997

Funding

AstraZeneca (Australia) NAEisai (Japan) NAIpsen (United States) NA
6 · The paper itself

Abstract

The management of early-stage hepatocellular carcinoma (HCC) is complex, with multiple treatment strategies available. There is a paucity of literature regarding variations in the patterns of care and outcomes between transplant and non-transplant centres. We conducted this real-world multi-centre cohort study in two liver cancer referral centres with an integrated liver transplant program and an additional eight non-transplant HCC referral centres across Australia to identify variation in patterns of care and key survival outcomes. Patients with stage Barcelona Clinic Liver Cancer (BCLC) 0/A HCC, first diagnosed between 1 January 2016 and 31 December 2020, who were managed at a participating site, were included in the study. Patients were excluded if they had a history of prior HCC or if they received upfront liver transplantation. A total of 887 patients were included in the study, with 433 patients managed at a liver cancer centre with a transplant program (LTC) and 454 patients managed at a non-transplant centre (NTC). Management at an LTC did not significantly predict allocation to resection (adjusted OR 0.75, 95% CI 0.50 to 1.11,

Indexed as

earlyhepatocellular carcinomapatterns of caresurvivaltransplant centre

Identifiers

PMID38893086
PMCPMC11171392

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.