Evidence map›Paper›PMID 38892884›Full record

ReviewJournal of clinical medicine2024

Understanding the Role of Female Genital Tract Microbiome in Recurrent Implantation Failure.

Anastasios Lafioniatis, Athina A Samara, Peter K Makaritsis, Stefanos Dafopoulos, Sotirios Sotiriou, Konstantinos Dafopoulos

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anastasios LafioniatisDepartment of Obstetrics and Gynecology, University Hospital of Larissa, 41110 Larissa, Greece.
Athina A SamaraDepartment of Obstetrics and Gynecology, University Hospital of Larissa, 41110 Larissa, Greece.ORCID 0000-0002-6177-7281
Peter K MakaritsisDepartment of Obstetrics and Gynecology, University Hospital of Larissa, 41110 Larissa, Greece.
Stefanos DafopoulosDepartment of Obstetrics and Gynecology, University Hospital of Larissa, 41110 Larissa, Greece.
Sotirios SotiriouDepartment of Embryology, Faculty of Medicine, University of Thessaly, 41110 Larissa, Greece.ORCID 0000-0002-9466-6086
Konstantinos DafopoulosDepartment of Obstetrics and Gynecology, University Hospital of Larissa, 41110 Larissa, Greece.ORCID 0000-0001-9991-8097

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The realization of the role of the microbiome of the female reproductive tract in health and disease has opened numerous possibilities for the scientific examination of the intertwining role between the human host and its microbiota. The imbalance in the composition of the microbial communities of the vagina and uterus is now recognized as a risk factor for many complications in pregnancy and according to the data from numerous studies, it is possible for this imbalance to play a crucial role in creating a hostile endometrial environment, and therefore, contributing to the etiology of recurrent implantation failure. Nevertheless, our current understanding of these complicated biological phenomena is far from complete, and in the future, there needs to be a systematic and thorough investigation of the diagnosis and therapy of this condition. This will enable scientists who engage in the field of assisted reproduction technologies to accurately identify and cure women in whom dysbiosis hinders the achievement of a healthy pregnancy.

Indexed as

IVFlactobacillusmicrobiomemicrobiotaRIF

Identifiers

PMID38892884
PMCPMC11172434

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.