Evidence map›Paper›PMID 38892714›Full record

ReviewNutrients2024

Multimodal Prehabilitation for Patients with Crohn's Disease Scheduled for Major Surgery: A Narrative Review.

Camilla Fiorindi, Francesco Giudici, Giuseppe Dario Testa, Lorenzo Foti, Sara Romanazzo, Cristina Tognozzi, Giovanni Mansueto, Stefano Scaringi, Francesca Cuffaro, Anita Nannoni and 2 more

Abstract readReview
In one paragraph

Review in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. [Position paper on prehabilitation in Germany].Chirurgie (Heidelberg, Germany) · 2026
    Review
  2. Observational
  3. Prehabilitation for Inflammatory Bowel Disease Surgery.Gastroenterology & hepatology · 2025
    Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Camilla FiorindiDepartment of Health Science, University of Firenze, Azienda Ospedaliero Universitaria Careggi, Largo Brambilla 3, 50139 Florence, Italy.ORCID 0000-0003-1387-0446
Francesco GiudiciDepartment of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 6, 50135 Florence, Italy.ORCID 0000-0002-6879-5685
Giuseppe Dario TestaMultimodal Prehabilitation Center, Azienda Ospedaliera Universitaria Careggi, Largo Brambilla 6, 50135 Florence, Italy.ORCID 0000-0002-9157-3781
Lorenzo FotiMultimodal Prehabilitation Center, Azienda Ospedaliera Universitaria Careggi, Largo Brambilla 6, 50135 Florence, Italy.ORCID 0009-0008-7335-9854
Sara RomanazzoDepartment of Health Science, University of Firenze, Azienda Ospedaliero Universitaria Careggi, Largo Brambilla 3, 50139 Florence, Italy.
Cristina TognozziDepartment of Health Science, University of Firenze, Azienda Ospedaliero Universitaria Careggi, Largo Brambilla 3, 50139 Florence, Italy.
Giovanni MansuetoDepartment of Health Science, University of Firenze, Azienda Ospedaliero Universitaria Careggi, Largo Brambilla 3, 50139 Florence, Italy.
Stefano ScaringiDepartment of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 6, 50135 Florence, Italy.
Francesca CuffaroDepartment of Health Science, University of Firenze, Azienda Ospedaliero Universitaria Careggi, Largo Brambilla 3, 50139 Florence, Italy.
Anita NannoniDepartment of Health Science, University of Firenze, Azienda Ospedaliero Universitaria Careggi, Largo Brambilla 3, 50139 Florence, Italy.
Mattias SoopDepartment for IBD and Intestinal Failure Surgery, Karolinska University Hospital, SE 177 76 Stockholm, Sweden.ORCID 0000-0003-4287-6978
Gabriele BaldiniDepartment of Health Science, University of Firenze, Azienda Ospedaliero Universitaria Careggi, Largo Brambilla 3, 50139 Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Approximately 15-50% of patients with Crohn's disease (CD) will require surgery within ten years following the diagnosis. The management of modifiable risk factors before surgery is essential to reduce postoperative complications and to promote a better postoperative recovery. Preoperative malnutrition reduced functional capacity, sarcopenia, immunosuppressive medications, anemia, and psychological distress are frequently present in CD patients. Multimodal prehabilitation consists of nutritional, functional, medical, and psychological interventions implemented before surgery, aiming at optimizing preoperative status and improve postoperative recovery. Currently, studies evaluating the effect of multimodal prehabilitation on postoperative outcomes specifically in CD are lacking. Some studies have investigated the effect of a single prehabilitation intervention, of which nutritional optimization is the most investigated. The aim of this narrative review is to present the physiologic rationale supporting multimodal surgical prehabilitation in CD patients waiting for surgery, and to describe its main components to facilitate their adoption in the preoperative standard of care.

Indexed as

Crohn DiseasePostoperative ComplicationsPreoperative CareHumansMalnutritionNutritional StatusPreoperative ExerciseCrohn’s diseaseEnhanced Recovery After Surgery (ERAS)multimodalnutritionprehabilitationsurgery

Identifiers

PMID38892714
PMCPMC11174506

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.