Evidence map›Paper›PMID 38892621›Full record

Trial reportNutrients2024

Effects of Resistance Exercise and Essential Amino Acid Intake on Muscle Quality, Myokine, and Inflammation Factors in Young Adult Males.

Deokhwa Jeong, Kyumin Park, Jinseok Lee, Jiye Choi, Haifeng Du, Hyeongmo Jeong, Liangliang Li, Kenji Sakai, Sunghwun Kang

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Trial
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  4. Trial
  5. Article
  6. Enzymatic Hydrolysates fromMarine drugs · 2026
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Exerkines and myokines in aging sarcopenia.Frontiers in endocrinology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Deokhwa JeongDepartment of Smart Health Science and Technology, Kangwon National University, Chuncheon 24341, Gangwon-do, Republic of Korea.
Kyumin ParkCenter for Sports Science in Gangwon, Chuncheon 24239, Gangwon-do, Republic of Korea.
Jinseok LeeDepartment of Sport Science, Kangwon National University, Chuncheon 24341, Gangwon-do, Republic of Korea.ORCID 0000-0003-1142-0740
Jiye ChoiDepartment of Smart Health Science and Technology, Kangwon National University, Chuncheon 24341, Gangwon-do, Republic of Korea.
Haifeng DuDepartment of Smart Health Science and Technology, Kangwon National University, Chuncheon 24341, Gangwon-do, Republic of Korea.
Hyeongmo JeongDepartment of Sport Science, Kangwon National University, Chuncheon 24341, Gangwon-do, Republic of Korea.
Liangliang LiDepartment of Sport Science, Kangwon National University, Chuncheon 24341, Gangwon-do, Republic of Korea.
Kenji SakaiChemicals & Life Science Division, Nagase Korea Corporation, Seoul 04527, Republic of Korea.
Sunghwun KangDepartment of Smart Health Science and Technology, Kangwon National University, Chuncheon 24341, Gangwon-do, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecently, many studies have been devoted to discovering nutrients for exercise-like effects. Resistance exercise and the intake of essential amino acids (EAAs) are known to be factors that can affect muscle mass and strength improvement. The purpose of this study was to investigate changes in muscle quality, myokines, and inflammation in response to resistance exercise and EAA supplementation.

methodsThirty-four males volunteered to participate in this study. They were assigned to four groups: (1) placebo (CO), (2) resistance exercise (RE), (3) EAA supplementation, and (4) RE + EAA supplementation. Body composition, muscle quality, myokines, and inflammation were measured at baseline and four weeks after treatment.

resultsLean body fat had decreased in both RE and RE + EAA groups. Lean body mass had increased in only the RE + EAA group. In all groups except for CO, irisin, myostatin A, and TNF-α levels had decreased. The grip strength of the right hand and trunk flexion peak torque increased in the RE group. The grip strength of the left hand, trunk flexion peak torque, and knee flexion peak torque of the left leg were increased in RE + EAA.

conclusionsRE, EAA, and RE + EAA could effectively improve the muscle quality, myokine, and inflammation factors of young adult males. This finding highlights the importance of resistance exercise and amino acid intake.

Indexed as

Amino Acids, EssentialBody CompositionDietary SupplementsInflammationMuscle, SkeletalResistance TrainingAdultFibronectinsHand StrengthHumansMaleMuscle StrengthMyokinesMyostatinTumor Necrosis Factor-alphaYoung AdultAmino Acids, EssentialFibronectinsFNDC5 protein, humanMyokinesMyostatinTumor Necrosis Factor-alphaessential amino acidsinflammationmuscle qualitymyokinesresistance exercise

Identifiers

PMID38892621
PMCPMC11174838

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.