Evidence map›Paper›PMID 38892548›Full record

ArticleNutrients2024

Supplementation of Seaweed Extracts to the Diet Reduces Symptoms of Alzheimer's Disease in the APPswePS1ΔE9 Mouse Model.

Nikita Martens, Na Zhan, Sammie C Yam, Frank P J Leijten, Marcella Palumbo, Martien Caspers, Assia Tiane, Silvia Friedrichs, Yanlin Li, Leonie van Vark-van der Zee and 9 more

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Holdfast-Derived Lipid Extract from the Patagonian MacroalgaPharmaceuticals (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Nikita MartensDepartment of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands.ORCID 0000-0001-6382-3379
Na ZhanDepartment of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands.
Sammie C YamDepartment of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands.
Frank P J LeijtenDepartment of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands.
Marcella PalumboDepartment of Food and Drug, University of Parma, 43124 Parma, Italy.
Martien CaspersDepartment of Microbiology and Systems Biology, The Netherlands Organization for Applied Scientific Research (TNO), 2333 BE Leiden, The Netherlands.ORCID 0000-0002-0248-4008
Assia TianeDepartment of Neuroscience, Biomedical Research Institute, Faculty of Medicine and Life Sciences, Hasselt University, B-3590 Hasselt, Belgium.ORCID 0000-0003-3931-8254
Silvia FriedrichsInstitute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, D-53127 Bonn, Germany.
Yanlin LiDepartment of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands.
Leonie van Vark-van der ZeeDepartment of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands.ORCID 0009-0008-7660-3330
Gardi VoortmanDepartment of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands.
Francesca ZimettiDepartment of Food and Drug, University of Parma, 43124 Parma, Italy.ORCID 0000-0002-6665-263X
Dick JaarsmaDepartment of Neuroscience, Erasmus University Medical Center, 3015 CN Rotterdam, The Netherlands.
Lars VerschurenDepartment of Microbiology and Systems Biology, The Netherlands Organization for Applied Scientific Research (TNO), 2333 BE Leiden, The Netherlands.ORCID 0000-0002-7847-9037
Johan W JonkerDepartment of Pediatrics, Section of Molecular Metabolism and Nutrition, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.ORCID 0000-0002-3919-5437
Folkert KuipersDepartment of Pediatrics, Section of Molecular Metabolism and Nutrition, University Medical Center Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.ORCID 0000-0003-2518-737X
Dieter LütjohannInstitute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, D-53127 Bonn, Germany.ORCID 0000-0002-7941-8308
Tim VanmierloDepartment of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands.ORCID 0000-0003-2912-0578
Monique T MulderDepartment of Internal Medicine, Section Pharmacology and Vascular Medicine, Erasmus University Medical Center, 3015 GE Rotterdam, The Netherlands.

Funding

Alzheimer Forschung Initiative AFI-18024CBAlzheimer Forschung Initiative AFI-22034CBAlzheimer Nederland WE.03-2018-06 ANAlzheimer Nederland WE.03-2022-06Alzheimer Nederland WE.15-2021-08Dutch Research Council 16437Ministry of University and Research DN. 1553 11.10.2022
6 · The paper itself

Abstract

We previously demonstrated that diet supplementation with seaweed

Indexed as

Alzheimer DiseaseDietary SupplementsDisease Models, AnimalSeaweedAmyloid beta-Protein PrecursorAnimalsCholesterolHippocampusHumansMaleMiceMice, TransgenicPlant ExtractsPlaque, AmyloidSargassumtau ProteinsAmyloid beta-Protein PrecursorCholesterolPlant Extractstau ProteinsAlzheimer’s diseasecholesterol metabolisminflammationliver X receptorsoxyphytosterolsseaweed

Identifiers

PMID38892548
PMCPMC11174572

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.