Evidence map›Paper›PMID 38892539›Full record

Trial reportNutrients2024

Optimizing Recovery in Elderly Patients: Anabolic Benefits of Glucose Supplementation during the Rehydration Period.

Ondrej Sobotka, Vojtech Mezera, Vladimir Blaha, Pavel Skorepa, Joao Fortunato, Lubos Sobotka

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ondrej Sobotka3rd Department of Internal Medicine-Metabolism and Gerontology, University Hospital Hradec Kralove, 500 05 Hradec Kralove, Czech Republic.ORCID 0000-0002-6453-148X
Vojtech Mezera3rd Department of Internal Medicine-Metabolism and Gerontology, University Hospital Hradec Kralove, 500 05 Hradec Kralove, Czech Republic.ORCID 0000-0002-8679-5208
Vladimir Blaha3rd Department of Internal Medicine-Metabolism and Gerontology, University Hospital Hradec Kralove, 500 05 Hradec Kralove, Czech Republic.ORCID 0000-0001-8088-9919
Pavel Skorepa3rd Department of Internal Medicine-Metabolism and Gerontology, University Hospital Hradec Kralove, 500 05 Hradec Kralove, Czech Republic.ORCID 0000-0002-9401-1848
Joao Fortunato3rd Department of Internal Medicine-Metabolism and Gerontology, University Hospital Hradec Kralove, 500 05 Hradec Kralove, Czech Republic.
Lubos Sobotka3rd Department of Internal Medicine-Metabolism and Gerontology, University Hospital Hradec Kralove, 500 05 Hradec Kralove, Czech Republic.

Funding

Aqualife Institute n/aCharles University: Cooperatio No. 8404413Ministry of Defence of the Czech Republic DZRO-FVZ22-KLINIKA II MH CZ - DRO (UHHK, 00179906)
6 · The paper itself

Abstract

backgroundSince many acutely admitted older adults display signs of dehydration, treatment using balanced crystalloids is an important part of medical care. Additionally, many of these patients suffer from chronic malnutrition. We speculated that the early addition of glucose might ameliorate the hospital-related drop of caloric intake and modify their catabolic status.

methodsWe included patients 78 years and older, admitted acutely for non-traumatic illnesses. The patients were randomized into either receiving balanced crystalloid (PlasmaLyte; group P) or balanced crystalloid enriched with 100 g of glucose per liter (group G). The information about fluid balance and levels of minerals were collected longitudinally.

resultsIn the G group, a significantly higher proportion of patients developed signs of refeeding syndrome, i.e., drops in phosphates, potassium and/or magnesium when compared to group P (83.3 vs. 16.7%,

conclusionThe short-term administration of balanced crystalloids with glucose induced an anabolic shift of electrolytes in acutely admitted older adults.

Indexed as

Fluid TherapyGlucoseAgedAged, 80 and overCrystalloid SolutionsDehydrationDietary SupplementsFemaleHospital MortalityHumansMaleRefeeding SyndromeWater-Electrolyte BalanceCrystalloid SolutionsGlucosedehydrationglucosemalnutritionrefeeding syndrome

Identifiers

PMID38892539
PMCPMC11173922

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.