Evidence map›Paper›PMID 38892510›Full record

ArticleNutrients2024

Feasibility and Safety of the Early Introduction of Allergenic Foods in Asian Infants with Eczema.

Daisuke Harama, Mayako Saito-Abe, Sayaka Hamaguchi, Tatsuki Fukuie, Yukihiro Ohya, Kiwako Yamamoto-Hanada

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daisuke HaramaAllergy Center, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo 157-8535, Japan.ORCID 0000-0002-2967-6739
Mayako Saito-AbeAllergy Center, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo 157-8535, Japan.ORCID 0000-0002-8845-7034
Sayaka HamaguchiAllergy Center, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo 157-8535, Japan.
Tatsuki FukuieAllergy Center, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo 157-8535, Japan.ORCID 0000-0003-4962-2137
Yukihiro OhyaAllergy Center, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo 157-8535, Japan.ORCID 0000-0002-1560-3942
Kiwako Yamamoto-HanadaAllergy Center, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo 157-8535, Japan.ORCID 0000-0003-1288-9620

Funding

AMED JP24gn0110078h0002JSPS KAKENHI 23H03320National Center For Child Health and Development 2023B-14 and 2022E-1
6 · The paper itself

Abstract

backgroundThere is a lack of data regarding the early introduction of the consumption of allergenic food among Asian infants.

methodsWe examined infants who had early-onset eczema before 6 months of age and received instructions from certified allergists for the early introduction of hen's eggs, milk, wheat, peanuts, and tree nuts.

resultsThe consumption rates of hen's eggs were 100% at 24 months. For peanuts and walnuts, the consumption rate was moderate at 12 months (48.5% and 30.3%, respectively), but by 24 months, it had progressed to 78.8% and 81.3%, respectively. In contrast, cashews remained at lower levels than other allergens at 20.7% at 12 months and 41.4% at 24 months. No adverse events related to early introductions occurred.

conclusionsIn infants with eczema, allergenic foods could be introduced early and well tolerated in Asian infants. However, having eczema may indicate a predisposition to food allergies, so caution is necessary when introducing allergenic foods. The early introduction of peanuts and tree nuts was still more challenging in real-world practice in Asia as well as in Western countries.

Indexed as

AllergensEczemaFood HypersensitivityArachisAsian PeopleChild, PreschoolEggsFeasibility StudiesFemaleHumansInfantMaleNutsAllergensearly introductioneczemafood allergyinfant

Identifiers

PMID38892510
PMCPMC11174384

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.