Evidence map›Paper›PMID 38892439›Full record

ArticleInternational journal of molecular sciences2024

Enhancing Machine-Learning Prediction of Enzyme Catalytic Temperature Optima through Amino Acid Conservation Analysis.

Yinyin Cao, Boyu Qiu, Xiao Ning, Lin Fan, Yanmei Qin, Dong Yu, Chunhe Yang, Hongwu Ma, Xiaoping Liao, Chun You

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yinyin CaoCollege of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, China.ORCID 0009-0006-9986-9065
Boyu QiuTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.
Xiao NingTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.
Lin FanTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.
Yanmei QinTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.
Dong YuCollege of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, China.
Chunhe YangCollege of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, China.
Hongwu MaTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.ORCID 0000-0001-5325-2314
Xiaoping LiaoTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.ORCID 0000-0002-9852-910X
Chun YouTianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin 300308, China.ORCID 0000-0003-2305-336X

Funding

National Key R&D Program of China 2023YFA0914000 and 2021YFA0910601, to C.YNational Natural Science Foundation of China 12326611, to L.X.National Natural Science Foundation of China 32271473, to C.Y.
6 · The paper itself

Abstract

Enzymes play a crucial role in various industrial production and pharmaceutical developments, serving as catalysts for numerous biochemical reactions. Determining the optimal catalytic temperature (

Indexed as

Amino AcidsMachine LearningTemperatureAlgorithmsAmino Acid SequenceCatalysisConserved SequenceEnzyme StabilityPhosphoric Monoester HydrolasesAmino AcidsPhosphoric Monoester Hydrolasesconserved amino acidsmachine learningmultiple sequence alignmentoptimal catalytic temperaturephosphatase

Identifiers

PMID38892439
PMCPMC11173260

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.