Evidence map›Paper›PMID 38892328›Full record

ArticleInternational journal of molecular sciences2024

The Multifaceted Actions of PVP-Curcumin for Treating Infections.

Magdalena Metzger, Stefan Manhartseder, Leonie Krausgruber, Lea Scholze, David Fuchs, Carina Wagner, Michaela Stainer, Johannes Grillari, Andreas Kubin, Lionel Wightman and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Multimodal Inhibition ofJournal of agricultural and food chemistry · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Magdalena MetzgerLudwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA, 1200 Vienna, Austria.ORCID 0000-0003-2203-2049
Stefan ManhartsederLudwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA, 1200 Vienna, Austria.
Leonie KrausgruberLudwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA, 1200 Vienna, Austria.
Lea ScholzeLudwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA, 1200 Vienna, Austria.
David FuchsLudwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA, 1200 Vienna, Austria.
Carina WagnerLudwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA, 1200 Vienna, Austria.
Michaela StainerLudwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA, 1200 Vienna, Austria.
Johannes GrillariLudwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA, 1200 Vienna, Austria.ORCID 0000-0001-5474-6332
Andreas KubinPlanta Naturstoffe Vertriebs GmbH, 1230 Vienna, Austria.
Lionel WightmanPlanta Naturstoffe Vertriebs GmbH, 1230 Vienna, Austria.
Peter DungelLudwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA, 1200 Vienna, Austria.

Funding

Austrian Research Promotion Agency 900408
6 · The paper itself

Abstract

Curcumin is a natural compound that is considered safe and may have potential health benefits; however, its poor stability and water insolubility limit its therapeutic applications. Different strategies aim to increase its water solubility. Here, we tested the compound PVP-curcumin as a photosensitizer for antimicrobial photodynamic therapy (aPDT) as well as its potential to act as an adjuvant in antibiotic drug therapy. Gram-negative

Indexed as

Anti-Bacterial AgentsCiprofloxacinCurcuminPhotosensitizing AgentsRec A RecombinasesDNA-Binding ProteinsEscherichia coliEscherichia coli K12Escherichia coli ProteinsLightMicrobial Sensitivity TestsPhotochemotherapyPovidoneSOS Response, GeneticsAnti-Bacterial AgentsCiprofloxacinCurcuminDNA-Binding ProteinsEscherichia coli ProteinsPhotosensitizing AgentsPovidonerecA protein, E coliRec A Recombinasesantimicrobial photodynamic therapyantimicrobial resistancebacterial SOS response

Identifiers

PMID38892328
PMCPMC11172534

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.