Evidence map›Paper›PMID 38892226›Full record

ArticleInternational journal of molecular sciences2024

Evaluation of In Vitro Synergistic Effects of Tetracycline with Alkaloid-Related Compounds against Diarrhoeic Bacteria.

Hayford Osei-Owusu, Johana Rondevaldova, Marketa Houdkova, Tomas Kudera, Tersia Needham, Anna Mascellani, Ladislav Kokoska

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Can Nature Overcome Invasive Gastrointestinal Infections?International journal of molecular sciences · 2025
    Review
  3. Biological Activities ofAntibiotics (Basel, Switzerland) · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hayford Osei-OwusuDepartment of Crop Sciences and Agroforestry, Faculty of Tropical AgriSciences, Czech University of Life Sciences Prague, Kamycka 129, Suchdol, 16500 Prague, Czech Republic.
Johana RondevaldovaDepartment of Crop Sciences and Agroforestry, Faculty of Tropical AgriSciences, Czech University of Life Sciences Prague, Kamycka 129, Suchdol, 16500 Prague, Czech Republic.ORCID 0000-0002-6142-2309
Marketa HoudkovaDepartment of Crop Sciences and Agroforestry, Faculty of Tropical AgriSciences, Czech University of Life Sciences Prague, Kamycka 129, Suchdol, 16500 Prague, Czech Republic.
Tomas KuderaDepartment of Crop Sciences and Agroforestry, Faculty of Tropical AgriSciences, Czech University of Life Sciences Prague, Kamycka 129, Suchdol, 16500 Prague, Czech Republic.
Tersia NeedhamDepartment of Animal Science and Food Processing, Faculty of Tropical AgriSciences, Czech University of Life Sciences Prague, Kamycka 129, Suchdol, 16500 Prague, Czech Republic.ORCID 0000-0001-9557-3335
Anna MascellaniDepartment of Food Science, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, Kamycka 129, Suchdol, 16500 Prague, Czech Republic.
Ladislav KokoskaDepartment of Crop Sciences and Agroforestry, Faculty of Tropical AgriSciences, Czech University of Life Sciences Prague, Kamycka 129, Suchdol, 16500 Prague, Czech Republic.ORCID 0000-0002-5677-692X

Funding

the Internal Grant Agency of the Faculty of Tropical AgriSciences IGA 20233109
6 · The paper itself

Abstract

Diarrhoea remains an important public health concern, particularly in developing countries, and has become difficult to treat because of antibacterial resistance. The development of synergistic antimicrobial agents appears to be a promising alternative treatment against diarrhoeic infections. In this study, the combined effect of tetracycline together with either nitroxoline, sanguinarine, or zinc pyrithione (representing various classes of plant-based compounds) was evaluated in vitro against selected diarrhoeic bacteria (

Indexed as

Anti-Bacterial AgentsDrug SynergismMicrobial Sensitivity TestsTetracyclineAlkaloidsBacteriaDiarrheaHumansNitroquinolinesOrganometallic CompoundsPyridinesAlkaloidsAnti-Bacterial AgentsNitroquinolinesnitroxolineOrganometallic CompoundsPyridinespyrithione zincTetracyclineantibacterial resistanceantimicrobial agentscombination therapydiarrhoeapathogenssynergistic effect

Identifiers

PMID38892226
PMCPMC11173066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.