In Silico Assessment of Chemical Disinfectants on Surface Proteins Unveiled Dissimilarity in Antiviral Efficacy and Suitability towards Pathogenic Viruses.

Diaiti Zure, Meng-Hau Sung, Abdul Rahim, Hsion-Wen Kuo

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Diaiti ZureDepartment of Environmental Science and Engineering, Tunghai University, Taichung 407224, Taiwan.ORCID 0000-0003-2263-6571

Meng-Hau SungDepartment of Environmental Science and Engineering, Tunghai University, Taichung 407224, Taiwan.

Abdul RahimDepartment of Environmental Science and Engineering, Tunghai University, Taichung 407224, Taiwan.

Hsion-Wen KuoDepartment of Environmental Science and Engineering, Tunghai University, Taichung 407224, Taiwan.

Funding

Ministry of Science and Technology, Taiwan MOST 105-2221-E-029-002 and 106-2221-E-029-003

6 · The paper itself

Abstract

Viral pathogens pose a substantial threat to public health and necessitate the development of effective remediation and antiviral strategies. This short communication aimed to investigate the antiviral efficacy of disinfectants on the surface proteins of human pathogenic viruses. Using in silico modeling, the ligand-binding energies (LBEs) of selected disinfectants were predicted and combined with their environmental impacts and costs through an eco-pharmaco-economic analysis (EPEA). The results revealed that the binding affinities of chemical disinfectants to viral proteins varied significantly (

Indexed as

Antiviral AgentsDisinfectantsRutinComputer SimulationHumansMembrane ProteinsMolecular Docking SimulationProtein BindingViral ProteinsVirusesAntiviral AgentsDisinfectantsMembrane ProteinsRutinViral Proteinsantiviral efficacyeco-pharmaco-economicin silico assessmentrutinsustainability

Identifiers

PMID38892197

DOI10.3390/ijms25116009

PMCPMC11172749

What OpenQuestion holds

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LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.