Evidence map›Paper›PMID 38892106›Full record

ArticleInternational journal of molecular sciences2024

Fatty Acid Synthase as Interacting Anticancer Target of the Terpenoid Myrianthic Acid Disclosed by MS-Based Proteomics Approaches.

Alessandra Capuano, Gilda D'Urso, Erica Gazzillo, Gianluigi Lauro, Maria Giovanna Chini, Maria Valeria D'Auria, Maria Grazia Ferraro, Federica Iazzetti, Carlo Irace, Giuseppe Bifulco and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alessandra CapuanoDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.
Gilda D'UrsoDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0002-4407-2781
Erica GazzilloDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.
Gianluigi LauroDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0001-5065-9717
Maria Giovanna ChiniDepartment of Biosciences and Territory, University of Molise, C.da Fonte Lappone, 86090 Pesche, Italy.
Maria Valeria D'AuriaDepartment of Pharmacy, University of Naples "Federico II", Via Domenico Montesano 49, 80131 Naples, Italy.
Maria Grazia FerraroDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-3022-1205
Federica IazzettiBiochem Lab, Department of Pharmacy, School of Medicine and Surgery, University of Naples "Federico II", Via Domenico Montesano 49, 80131 Naples, Italy.
Carlo IraceBiochem Lab, Department of Pharmacy, School of Medicine and Surgery, University of Naples "Federico II", Via Domenico Montesano 49, 80131 Naples, Italy.ORCID 0000-0002-5172-4573
Giuseppe BifulcoDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.
Agostino CasapulloDepartment of Pharmacy, University of Salerno, 84084 Fisciano, Italy.ORCID 0000-0002-2310-9426

Funding

FARB 2022 ORSA22727PRIN2022-PNRR project P2022CKMPW
6 · The paper itself

Abstract

This research focuses on the target deconvolution of the natural compound myrianthic acid, a triterpenoid characterized by an ursane skeleton isolated from the roots of

Indexed as

Molecular Docking SimulationProteomicsAntineoplastic AgentsCell Line, TumorCell ProliferationFatty Acid SynthasesHumansMass SpectrometryTerpenesTriterpenesAntineoplastic AgentsFatty Acid SynthasesTerpenesTriterpenesDARTSdrug discoveryfatty acid synthasefunctional proteomicsmolecular dockingpreclinical investigationst-LiP

Identifiers

PMID38892106
PMCPMC11172900

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.