Evidence map›Paper›PMID 38892052›Full record

ReviewInternational journal of molecular sciences2024

Applications of Stem Cell-Derived Extracellular Vesicles in Nerve Regeneration.

Burcak Yavuz, Esra Cansever Mutlu, Zubair Ahmed, Besim Ben-Nissan, Artemis Stamboulis

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  15. Extracellular Vesicles: Biology and Therapeutic Applications.International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Burcak YavuzVocational School of Health Services, Altinbas University, 34147 Istanbul, Turkey.ORCID 0000-0002-3555-4850
Esra Cansever MutluBiomaterials Research Group, School of Metallurgy and Materials, College of Engineering and Physical Science, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0003-1956-4474
Zubair AhmedNeuroscience & Ophthalmology, Institute of Inflammation and Ageing, University of Birmingham, Edgbaston B15 2TT, UK.ORCID 0000-0001-6267-6442
Besim Ben-NissanTranslational Biomaterials and Medicine Group, School of Life Sciences, University of Technology Sydney, P.O. Box 123, Broadway, NSW 2007, Australia.
Artemis StamboulisBiomaterials Research Group, School of Metallurgy and Materials, College of Engineering and Physical Science, University of Birmingham, Birmingham B15 2TT, UK.ORCID 0000-0002-8366-590X

Funding

College of Engineering and Physical Sciences, University of Birmingham NASRMRC2-NIHR NATUSEB Project 24212
6 · The paper itself

Abstract

Extracellular vesicles (EVs), including exosomes, microvesicles, and other lipid vesicles derived from cells, play a pivotal role in intercellular communication by transferring information between cells. EVs secreted by progenitor and stem cells have been associated with the therapeutic effects observed in cell-based therapies, and they also contribute to tissue regeneration following injury, such as in orthopaedic surgery cases. This review explores the involvement of EVs in nerve regeneration, their potential as drug carriers, and their significance in stem cell research and cell-free therapies. It underscores the importance of bioengineers comprehending and manipulating EV activity to optimize the efficacy of tissue engineering and regenerative therapies.

Indexed as

Extracellular VesiclesNerve RegenerationStem CellsAnimalsExosomesHumansRegenerative MedicineTissue Engineeringblood-brain barrierexosomenerve regenerationnon-coding RNAstraumatic brain injury

Identifiers

PMID38892052
PMCPMC11172915

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.