Evidence map›Paper›PMID 38892022›Full record

ArticleInternational journal of molecular sciences2024

Effect of Cigarette Smoking on Clinical and Molecular Endpoints in COPD Patients.

Patrizia Russo, Francesca Milani, Antonio De Iure, Stefania Proietti, Dolores Limongi, Carla Prezioso, Paola Checconi, Vincenzo Zagà, Federica Novazzi, Fabrizio Maggi and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Premature mortality from respiratory disease attributable to PMInternational journal of occupational medicine and environmental health · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Patrizia RussoDepartment of Human Sciences and Promotion of the Quality of Life, San Raffaele University, Via di Val Cannuta 247, 00166 Rome, Italy.
Francesca MilaniDepartment of Human Sciences and Promotion of the Quality of Life, San Raffaele University, Via di Val Cannuta 247, 00166 Rome, Italy.
Antonio De IureDepartment of Human Sciences and Promotion of the Quality of Life, San Raffaele University, Via di Val Cannuta 247, 00166 Rome, Italy.
Stefania ProiettiDepartment of Human Sciences and Promotion of the Quality of Life, San Raffaele University, Via di Val Cannuta 247, 00166 Rome, Italy.
Dolores LimongiDepartment of Human Sciences and Promotion of the Quality of Life, San Raffaele University, Via di Val Cannuta 247, 00166 Rome, Italy.
Carla PreziosoDepartment of Human Sciences and Promotion of the Quality of Life, San Raffaele University, Via di Val Cannuta 247, 00166 Rome, Italy.ORCID 0000-0002-8377-0742
Paola ChecconiDepartment of Human Sciences and Promotion of the Quality of Life, San Raffaele University, Via di Val Cannuta 247, 00166 Rome, Italy.ORCID 0000-0001-7518-5730
Vincenzo ZagàItalian Society of Tabaccology (SITAB), Via G. Scalia 39, 00136 Rome, Italy.
Federica NovazziDepartment of Medicine and Surgery, University of Insubria, Via Ravasi 2, 21100 Varese, Italy.ORCID 0000-0002-2741-8840
Fabrizio MaggiIstituto Nazionale Malattie Infettive Lazzaro Spallanzani, Via Portuense 292, 00149 Rome, Italy.ORCID 0000-0001-7489-5271
Guido AntonelliVirology Laboratory, Department of Molecular Medicine, Sapienza University, Viale Porta Tiburtina 28, 00185 Rome, Italy.ORCID 0000-0002-2533-2939
Stefano BonassiDepartment of Human Sciences and Promotion of the Quality of Life, San Raffaele University, Via di Val Cannuta 247, 00166 Rome, Italy.ORCID 0000-0003-3833-6717

Funding

Ministero dell'Università e della Ricerca. PRIN: PROGETTI DI RICERCA DI RILEVANTE INTERESSE NAZIONALE B53D23003760006/ G53D23000700001/G53D2300054
6 · The paper itself

Abstract

Cigarette smoking is a primary contributor to mortality risks and is associated with various diseases. Among these, COPD represents a significant contributor to global mortality and disability. The objective of this study is to investigate the effect of smoking on a selected battery of variables, with an emphasis on DNA damage. A total of 87 elderly patients diagnosed with COPD, divided into three groups based on their smoking history (current, former, never-smokers), were evaluated using a cross-sectional approach. Clinical features including mortality and inflammatory/oxidative parameters (Lymphocytes/Monocytes, Neutrophils/Lymphocytes, Platelets/Lymphocytes ratio), SII, MDA, 8-Oxo-dG, and IL6 (ELISA assay), as well as DNA damage (comet assay), were investigated. Virus infection, i.e., influenza A virus subtype H1N1, JC polyomavirus (JCPyV), BK polyomavirus (BKPyV), and Torquetenovirus (TTV), was also tested. Current smokers exhibit higher levels of comorbidity (CIRS;

Indexed as

Cigarette SmokingDNA DamageOxidative StressPulmonary Disease, Chronic ObstructiveAgedBiomarkersCross-Sectional StudiesFemaleHumansInflammationMaleMiddle AgedBiomarkerscigarette smokingCOPDDNA damageinflammationmortalityvirus

Identifiers

PMID38892022
PMCPMC11172087

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.