ArticleInternational journal of molecular sciences2024
Increased Absorption of Thyroxine in a Murine Model of Hypothyroidism Using Water/CO
Maria Cecilia Opazo, Osvaldo Yañez, Valeria Márquez-Miranda, Johana Santos, Maximiliano Rojas, Ingrid Araya-Durán, Daniel Aguayo, Matías Leal, Yorley Duarte, Jorge Kohanoff and 1 more
Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
11 authors.
Maria Cecilia OpazoFacultad de Medicina Veterinaria y Agronomía, Instituto de Ciencias Naturales, Universidad de las Américas, Santiago 7500975, Chile.
Osvaldo YañezNúcleo de Investigación en Data Science, Facultad de Ingeniería y Negocios, Universidad de las Américas, Santiago 7500975, Chile.ORCID 0000-0001-8993-9353
Valeria Márquez-MirandaCenter for Bioinformatics and Integrative Biology (CBIB), Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370146, Chile.
Johana SantosLaboratorio de Endocrino Inmunología, Millenium Institute on Immunology and Immunotherapy, Facultad de Ciencias de la Vida, Universidad Andrés Bello, Santiago 8370146, Chile.
Maximiliano RojasCenter for Bioinformatics and Integrative Biology (CBIB), Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370146, Chile.
Ingrid Araya-DuránCenter for Bioinformatics and Integrative Biology (CBIB), Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370146, Chile.
Daniel AguayoCenter for Bioinformatics and Integrative Biology (CBIB), Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370146, Chile.
Matías LealDepartamento de Química Orgánica y Fisicoquímica, Facultad de Ciencias Químicas y Farmacéuticas, Universidad de Chile, Santiago 8380494, Chile.ORCID 0000-0002-7145-1920
Yorley DuarteCenter for Bioinformatics and Integrative Biology (CBIB), Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370146, Chile.
Jorge KohanoffInstituto de Fusión Nuclear "Guillermo Velarde", Universidad Politécnica de Madrid, 28006 Madrid, Spain.ORCID 0000-0002-8237-7543
Fernando D González-NiloCenter for Bioinformatics and Integrative Biology (CBIB), Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago 8370146, Chile.ORCID 0000-0001-6857-3575
Funding
Gobierno de Chile MCO(Proyecto Fondecyt 11180739); FGN (Proyecto Fondecyt 1221498, FONDEF ID22I10344); YD (Proyecto Fondecyt 11201113), VMM (Fondecyt 11241081, FOVI230118), EPSRC grant EP/L025124/1..
6 · The paper itself
Abstract
Thyroxine (T4) is a drug extensively utilized for the treatment of hypothyroidism. However, the oral absorption of T4 presents certain limitations. This research investigates the efficacy of CO
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
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