Evidence map›Paper›PMID 38892003›Full record

ReviewInternational journal of molecular sciences2024

The Known, the Unknown and the Future of the Pathophysiology of Endometriosis.

Maria Ariadna Ochoa Bernal, Asgerally T Fazleabas

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
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  3. Review
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  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. How Women with Endometriosis Use Social Media for Support and Self-Management: An Analysis of Reddit Content.International journal of environmental research and public health · 2025
    Article
  16. Review
  17. Review
  18. Unraveling the Core of Endometriosis: The Impact of Endocrine Disruptors.International journal of molecular sciences · 2025
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Maria Ariadna Ochoa BernalDepartment of Obstetrics, Gynecology & Reproductive Biology, Michigan State University, Grand Rapids, MI 49503, USA.ORCID 0000-0002-9070-7135
Asgerally T FazleabasDepartment of Obstetrics, Gynecology & Reproductive Biology, Michigan State University, Grand Rapids, MI 49503, USA.

Funding

Modulation of the Receptive Endometrium by CGR01HD042280 · NICHD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FAZLEABAS, ASGERALLY T. · 2003 to 2020
$4.6M
Regulation of Endometriotic Lesion Development by NOTCH1R01HD099090 · NICHD · MICHIGAN STATE UNIVERSITY · PI FAZLEABAS, ASGERALLY T. · 2021 to 2025
$2.8M
Reproductive and Developmental Sciences Training Program - T32T32HD087166 · NICHD · MICHIGAN STATE UNIVERSITY · PI Ronald L Chandler, Keith E Latham · 2016 to 2026
$2.5M
Role of microRNA in the Pathophysiology of EndometriosisR01HD083273 · NICHD · MICHIGAN STATE UNIVERSITY · PI FAZLEABAS, ASGERALLY T. · 2016 to 2020
$1.8M
NICHD NIH HHS T32 HD087166NIH HHS 2T32HD087166-17A1NIH HHS 5R01HD042280-21A1NIH HHS 5R01HD083273-22A1NIH HHS 5R01HD099090-23A1
6 · The paper itself

Abstract

Endometriosis is one of the most common causes of chronic pelvic pain and infertility, affecting 10% of women of reproductive age. A delay of up to 9 years is estimated between the onset of symptoms and the diagnosis of endometriosis. Endometriosis is currently defined as the presence of endometrial epithelial and stromal cells at ectopic sites; however, advances in research on endometriosis have some authors believing that endometriosis should be re-defined as "a fibrotic condition in which endometrial stroma and epithelium can be identified". There are several theories on the etiology of the disease, but the origin of endometriosis remains unclear. This review addresses the role of microRNAs (miRNAs), which are naturally occurring post-transcriptional regulatory molecules, in endometriotic lesion development, the inflammatory environment within the peritoneal cavity, including the role that cytokines play during the development of the disease, and how animal models have helped in our understanding of the pathology of this enigmatic disease.

Indexed as

EndometriosisMicroRNAsAnimalsCytokinesDisease Models, AnimalEndometriumFemaleHumansCytokinesMicroRNAsbaboon modelcytokinesendometriosisfibrosisinfertilitymicroRNAmouse modeloriginspathophysiology

Identifiers

PMID38892003
PMCPMC11172035

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.