Evidence map›Paper›PMID 38891932›Full record

ArticleInternational journal of molecular sciences2024

4-O-Methylascochlorin Synergistically Enhances 5-Fluorouracil-Induced Apoptosis by Inhibiting the Wnt/β-Catenin Signaling Pathway in Colorectal Cancer Cells.

Min-Young Jo, Yun-Jeong Jeong, Kwon-Ho Song, Yung Hyun Choi, Taeg Kyu Kwon, Young-Chae Chang

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Min-Young JoResearch Institute of Biomedical Engineering and Department of Cell Biology, Daegu Catholic University School of Medicine, Daegu 42472, Republic of Korea.ORCID 0009-0008-8069-7624
Yun-Jeong JeongResearch Institute of Biomedical Engineering and Department of Cell Biology, Daegu Catholic University School of Medicine, Daegu 42472, Republic of Korea.
Kwon-Ho SongResearch Institute of Biomedical Engineering and Department of Cell Biology, Daegu Catholic University School of Medicine, Daegu 42472, Republic of Korea.
Yung Hyun ChoiDepartment of Biochemistry, College of Korean Medicine, Dong-Eui University, Busan 47227, Republic of Korea.ORCID 0000-0002-1454-3124
Taeg Kyu KwonDepartment of Immunology, School of Medicine, Keimyung University, Daegu 42601, Republic of Korea.ORCID 0000-0003-1204-2059
Young-Chae ChangResearch Institute of Biomedical Engineering and Department of Cell Biology, Daegu Catholic University School of Medicine, Daegu 42472, Republic of Korea.ORCID 0000-0003-2667-7303

Funding

National Research Foundation of Korea (NRF) Korean government (MSIT) 2022R1A4A5032702
6 · The paper itself

Abstract

4-O-Methyl-ascochlorin (MAC), a derivative of the prenyl-phenol antibiotic ascochlorin extracted from the fungus

Indexed as

Apoptosisbeta CateninCell ProliferationColorectal NeoplasmsDrug SynergismFluorouracilWnt Signaling PathwayCell Line, TumorDrug Resistance, NeoplasmHumansTOR Serine-Threonine Kinasesbeta CateninCTNNB1 protein, humanFluorouracilTOR Serine-Threonine Kinases4-O-methlyascochlorin5-fluorouracildrug-resistancesynergistic effectsβ-catenin

Identifiers

PMID38891932
PMCPMC11172374

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.