Evidence map›Paper›PMID 38891911›Full record

ArticleInternational journal of molecular sciences2024

Trimeric and Tetrameric Cationic Styryl Dyes as Novel Fluorescence and CD Probes for ds-DNA and ds-RNA.

Dijana Pavlović Saftić, Ivona Krošl Knežević, Fernando de Lera Garrido, Juan Tolosa, Dragomira Majhen, Ivo Piantanida, Joaquín Calixto García Martínez

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dijana Pavlović SaftićDivision of Organic Chemistry & Biochemistry, Ruđer Bošković Institute, 10000 Zagreb, Croatia.ORCID 0000-0002-0657-1635
Ivona Krošl KneževićDivision of Organic Chemistry & Biochemistry, Ruđer Bošković Institute, 10000 Zagreb, Croatia.
Fernando de Lera GarridoDepartment of Inorganic and Organic Chemistry and Biochemistry, Faculty of Pharmacy, Universidad de Castilla-La Mancha, C/José María Sánchez Ibáñez s/n, 02008 Albacete, Spain.ORCID 0000-0002-6052-0329
Juan TolosaDepartment of Inorganic and Organic Chemistry and Biochemistry, Faculty of Pharmacy, Universidad de Castilla-La Mancha, C/José María Sánchez Ibáñez s/n, 02008 Albacete, Spain.ORCID 0000-0002-6761-4301
Dragomira MajhenDivision of Molecular Biology, Ruđer Bošković Institute, 10000 Zagreb, Croatia.ORCID 0000-0003-0385-0900
Ivo PiantanidaDivision of Organic Chemistry & Biochemistry, Ruđer Bošković Institute, 10000 Zagreb, Croatia.ORCID 0000-0002-9933-446X
Joaquín Calixto García MartínezDepartment of Inorganic and Organic Chemistry and Biochemistry, Faculty of Pharmacy, Universidad de Castilla-La Mancha, C/José María Sánchez Ibáñez s/n, 02008 Albacete, Spain.ORCID 0000-0003-3321-4243

Funding

Croatian Science Foundation IP-2022-10-9829
6 · The paper itself

Abstract

The wide use of mono- or bis-styryl fluorophores in biomedical applications prompted the presented design and study of a series of trimeric and tetrameric homo-analogues, styryl moieties arranged around a central aromatic core. The interactions with the most common biorelevant targets, ds-DNA and ds-RNA, were studied by a set of spectrophotometric methods (UV-VIS, fluorescence, circular dichroism, thermal denaturation). All studied dyes showed strong light absorption in the 350-420 nm range and strongly Stokes-shifted (+100-160 nm) emission with quantum yields (

Indexed as

CationsCircular DichroismDNAFluorescent DyesRNA, Double-StrandedHumansNucleic Acid DenaturationSpectrometry, FluorescenceStyrenesCationsDNAFluorescent DyesRNA, Double-StrandedStyrenescell non-toxicitycircular dichroismDNA bindingfluorescenceRNA bindingstyryl dyes

Identifiers

PMID38891911
PMCPMC11171523

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.