Evidence map›Paper›PMID 38891899›Full record

ArticleInternational journal of molecular sciences2024

Poly (I:C)-Induced microRNA-30b-5p Negatively Regulates the JAK/STAT Signaling Pathway to Mediate the Antiviral Immune Response in Silver Carp (

Meng Liu, Huan Tang, Kun Gao, Xiqing Zhang, Zhenhua Ma, Yunna Jia, Zihan Yang, Muhammad Inam, Yunhang Gao, Guiqin Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Polyinosinic-polycytidylic acid modulatesJournal of dental sciences · 2025
    Article
  2. miR-212-5p Regulates PMInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Meng LiuDepartment of Veterinary Medicine, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Huan TangDepartment of Veterinary Medicine, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Kun GaoDepartment of Veterinary Medicine, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Xiqing ZhangDepartment of Veterinary Medicine, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Zhenhua MaDepartment of Veterinary Medicine, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Yunna JiaDepartment of Veterinary Medicine, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Zihan YangDepartment of Veterinary Medicine, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Muhammad InamDepartment of Veterinary Medicine, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Yunhang GaoDepartment of Veterinary Medicine, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.ORCID 0000-0001-5701-6685
Guiqin WangDepartment of Veterinary Medicine, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.
Xiaofeng ShanDepartment of Veterinary Medicine, College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China.

Funding

Jilin Provincial Department of Science and Technology Program 20210202049NCNational Natural Science Foundation of China No. 32273150the earmarked fund for China Agriculture Research System CARS-46
6 · The paper itself

Abstract

In aquaculture, viral diseases pose a significant threat and can lead to substantial economic losses. The primary defense against viral invasion is the innate immune system, with interferons (IFNs) playing a crucial role in mediating the immune response. With advancements in molecular biology, the role of non-coding RNA (ncRNA), particularly microRNAs (miRNAs), in gene expression has gained increasing attention. While the function of miRNAs in regulating the host immune response has been extensively studied, research on their immunomodulatory effects in teleost fish, including silver carp (

Indexed as

CarpsFish ProteinsMicroRNAsPoly I-CSignal TransductionAnimalsFish DiseasesGene Expression RegulationImmunity, InnateJanus KinasesSTAT Transcription FactorsFish ProteinsJanus KinasesMicroRNAsPoly I-CSTAT Transcription FactorsCRFB5IFNsinnate immunitymiR-30b-5ppoly (I:C)silver carp

Identifiers

PMID38891899
PMCPMC11172372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.