Evidence map›Paper›PMID 38891792›Full record

ReviewInternational journal of molecular sciences2024

The Biological Role of Platelet Derivatives in Regenerative Aesthetics.

Lorena Cristina Santos, Giselle Lobo Lana, Gabriel Silva Santos, Silvia Beatriz Coutinho Visoni, Rayssa Junqueira Brigagão, Napoliane Santos, Rafaela Sobreiro, Andreza da Cruz Silva Reis, Bruno Lima Rodrigues, Sabrina Ferrari and 2 more

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Article
  6. PDGF In Aesthetics: Hype Outpacing the Evidence?Journal of cosmetic dermatology · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lorena Cristina SantosBiomedical Science, Hospital das Clínicas de Goiás, Goiânia 74605-020, Brazil.
Giselle Lobo LanaOrthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, Brazil.
Gabriel Silva SantosOrthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, Brazil.ORCID 0000-0002-0549-6821
Silvia Beatriz Coutinho VisoniOrthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, Brazil.
Rayssa Junqueira BrigagãoOrthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, Brazil.
Napoliane SantosOrthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, Brazil.ORCID 0009-0002-8938-5498
Rafaela SobreiroOrthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, Brazil.
Andreza da Cruz Silva ReisOrthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, Brazil.
Bruno Lima RodriguesOrthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, Brazil.ORCID 0000-0002-5794-2950
Sabrina FerrariOrthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, Brazil.
Claudia Herrera TambeliInstitute of Biology, State University of Campinas (UNICAMP), Campinas 13083-862, Brazil.
José Fábio LanaOrthopedics, Brazilian Institute of Regenerative Medicine (BIRM), Indaiatuba 13334-170, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioproducts derived from platelets have been extensively used across various medical fields, with a recent notable surge in their application in dermatology and aesthetic procedures. These products, such as platelet-rich plasma (PRP) and platelet-rich fibrin (PRF), play crucial roles in inducing blood vessel proliferation through growth factors derived from peripheral blood. PRP and PRF, in particular, facilitate fibrin polymerization, creating a robust structure that serves as a reservoir for numerous growth factors. These factors contribute to tissue regeneration by promoting cell proliferation, differentiation, and migration and collagen/elastin production. Aesthetic medicine harnesses these effects for diverse purposes, including hair restoration, scar treatment, striae management, and wound healing. Furthermore, these biological products can act as adjuvants with other treatment modalities, such as laser therapy, radiofrequency, and microneedling. This review synthesizes the existing evidence, offering insights into the applications and benefits of biological products in aesthetic medicine.

Indexed as

Platelet-Rich FibrinPlatelet-Rich PlasmaRegenerative MedicineAnimalsBlood PlateletsCell ProliferationHumansRegenerationWound Healingaesthetic medicinegrowth factorsplatelet-rich fibrinplatelet-rich plasmatissue regeneration

Identifiers

PMID38891792
PMCPMC11172268

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.