Evidence map›Paper›PMID 38891751›Full record

ArticleAnimals : an open access journal from MDPI2024

Serum D-Lactate Concentrations in Dogs with Inflammatory Bowel Disease.

Giulia Maggi, Elisabetta Chiaradia, Alice Vullo, Matteo Seccaroni, Laura Valli, Sara Busechian, Domenico Caivano, Francesco Porciello, Sabrina Caloiero, Maria Chiara Marchesi

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giulia MaggiDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.ORCID 0009-0000-4697-1222
Elisabetta ChiaradiaDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.ORCID 0000-0002-0958-9187
Alice VulloDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.
Matteo SeccaroniDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.ORCID 0009-0000-7547-1139
Laura ValliIndependent Researcher, 23891 Rome, Italy.
Sara BusechianDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.ORCID 0000-0003-0616-4455
Domenico CaivanoDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.ORCID 0000-0001-8540-4853
Francesco PorcielloDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.
Sabrina CaloieroKennel Training Course Castiglione del Lago of Financial Guard, Via Lungolago 46, 06061 Castiglione del Lago, Italy.
Maria Chiara MarchesiDepartment of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 06126 Perugia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The D-enantiomer of lactic acid (D-lactate) is normally produced from bacterial fermentation in the gastrointestinal tract in mammals. In humans, increased D-lactate concentrations are related to gastrointestinal disease, including short bowel syndrome and malabsorptive syndrome. Similarly, increased D-lactate concentrations have been described in calves affected by diarrhea, in cats with gastrointestinal diseases, and in dogs with parvoviral enteritis. The purpose of the present study was to measure the serum D-lactate concentrations in dogs with inflammatory bowel disease (IBD). We retrospectively reviewed data from the database of the VTH of Perugia University, and dogs affected by IBD with serum samples stored at -80 °C were considered eligible for inclusion. A total of 18 dogs with IBD and 10 healthy dogs were included in the study. The dogs with IBD were divided into three subcategories based on the severity of the disease. Serum D-lactate concentrations (μM) were determined using a commercially available colorimetric assay kit (D-Lactate Colorimetric Assay Kit; Catalog #K667-100, BioVision Inc., Milpitas, CA, USA). Our results showed no significant difference (

Indexed as

canineD-lactatedysbiosisgastroenterologyinflammatory bowel disease

Identifiers

PMID38891751
PMCPMC11171325

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.