Evidence map›Paper›PMID 38891718›Full record

ArticleAnimals : an open access journal from MDPI2024

Establishing a Reference Interval for Fibroblast Growth Factor (FGF)-23 in Cats.

Sandra Lapsina, Jennifer von Luckner, Nicole Nagler, Simon Franz Müller, Elisabeth Müller, Ingo Schäfer

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sandra LapsinaLABOKLIN GmbH and Co. KG, Steubenstraße 4, 97688 Bad Kissingen, Germany.ORCID 0000-0001-8635-1327
Jennifer von LucknerLABOKLIN GmbH and Co. KG, Steubenstraße 4, 97688 Bad Kissingen, Germany.
Nicole NaglerLABOKLIN GmbH and Co. KG, Steubenstraße 4, 97688 Bad Kissingen, Germany.
Simon Franz MüllerLABOKLIN GmbH and Co. KG, Steubenstraße 4, 97688 Bad Kissingen, Germany.ORCID 0000-0002-5429-0088
Elisabeth MüllerLABOKLIN GmbH and Co. KG, Steubenstraße 4, 97688 Bad Kissingen, Germany.
Ingo SchäferLABOKLIN GmbH and Co. KG, Steubenstraße 4, 97688 Bad Kissingen, Germany.ORCID 0000-0001-9264-6607

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fibroblast growth factor (FGF)-23 is a phosphaturic hormone. An association between increasing FGF-23 levels and progression of chronic kidney disease (CKD) was documented in cats, dogs, and humans. The information regarding reference intervals (RIs) of FGF-23 in cats is limited. We aimed to establish RIs in a large cohort of clinically healthy cats and to investigate correlations with sex and age. A total of 118 cats with unremarkable complete blood count and serum chemistry profile were included. Clinically sick cats, cats with concurrent diseases, suspicion of CKD, or receiving renal diets were excluded. FGF-23 concentrations were measured with the FGF-23 ELISA Kit. RIs were calculated using the reference interval advisor software 2.1 (Microsoft Excel). FGF-23 concentrations were correlated with sex and age. The RI for FGF-23 concentrations spanned 85.8 to 387.0 pg/mL (90% confidence interval: lower limit 40.5 to 103.9 pg/mL, upper limit: 354.6 to 425.0 pg/mL). No significant relationships (r

Indexed as

chronic kidney diseaseclinical pathologydiagnosticsfeline

Identifiers

PMID38891718
PMCPMC11171358

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.