Evidence map›Paper›PMID 38891601›Full record

ArticleAnimals : an open access journal from MDPI2024

Supplementation of the Combination of Quercetin and Vitamin E Alleviates the Effects of Heat Stress on the Uterine Function and Hormone Synthesis in Laying Hens.

Xueqing Cao, Felix Kwame Amevor, Xiaxia Du, Youhao Wu, Dan Xu, Shuo Wei, Gang Shu, Jing Feng, Xiaoling Zhao

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Early-Phase Response of Broiler Breeders to 25-Hydroxyvitamin DAnimals : an open access journal from MDPI · 2026
    Article
  2. Effects ofAnimals : an open access journal from MDPI · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Effects of Dietary Ginger (Animals : an open access journal from MDPI · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xueqing CaoState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Felix Kwame AmevorState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0003-2682-1993
Xiaxia DuState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Youhao WuState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Dan XuState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Shuo WeiState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.
Gang ShuDepartment of Basic Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-0610-9635
Jing FengInstitute of Animal Husbandry and Veterinary Medicine, Tibet Academy of Agricultural and Animal Husbandry Science, Lhasa 851418, China.
Xiaoling ZhaoState Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-0633-4701

Funding

Central Guidance Local Free Exploration Project "Identification of Core Cell Subsets and Key Genes in Response to Chicken Lipid Derived Exosomes Regulating Abnormal Liver Lipid Metabolism 23ZYZYTS0346National Natural Science Foundation of China 32272870National Natural Science Foundation of China 32350410427Sichuan Province Central Guided Local Science and Technology Development Special Programme 23ZYZYTS0346The Sichuan Provincial Natural Science Foundation Outstanding Youth Science Fund Project "Construction of Spatial Transcription Atlas of Chicken Liver Before and After Shelling and Research on Metabolic Reprogramming Regulation Mechanism" 24NSFJQ0121
6 · The paper itself

Abstract

Chickens are sensitive to heat stress because their capacity to dissipate body heat is low. Hence, in chickens, excessive ambient temperature negatively influences their reproductive performance and health. Heat stress induces inflammation and oxidative stress, thereby rendering many reproductive organs dysfunctional. In this study, we evaluated the effects of the supplementation of dietary quercetin and vitamin E on the uterine function, eggshell quality via estrogen concentration, calcium metabolism, and antioxidant status of the uterus of laying hens under heat stress. The ambient temperature transformation was set at 34 ± 2 °C for 8 h/d (9:00 am-5:00 pm), which was followed by 22 °C to 28 °C for 16 h/d. Throughout the experiment, the relative humidity in the chicken's pen was at 50 to 65%. A total of 400 Tianfu breeder hens (120-days-old) were randomly divided into four dietary experimental groups, including basal diet (Control); basal diet + 0.4 g/kg quercetin; basal diet + 0.2 g/kg vitamin E; and basal diet + the combination of quercetin (0.4 g/kg) and vitamin E (0.2 g/kg). The results show that the combination of quercetin and vitamin E significantly increased the serum alkaline phosphatase levels and the antioxidant status of the uterus (

Indexed as

calcium metabolismheat stresshormone synthesisquercetin and vitamin Euterus

Identifiers

PMID38891601
PMCPMC11171397

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.