Evidence map›Paper›PMID 38891198›Full record

ArticleHealthcare (Basel, Switzerland)2024

Evaluation of the Oral Microbiome before and after Treatments for Halitosis with Photodynamic Therapy and Probiotics-Pilot Study.

Pamella de Barros Motta, Marcela Leticia Leal Gonçalves, Juliana Maria Altavista Sagretti Gallo, Ana Paula Taboada Sobral, Lara Jansiski Motta, Elaine Marcílio Santos, David José Casimiro de Andrade, Cinthya Cosme Gutierrez Duran, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari and 2 more

Abstract read
In one paragraph

Article in Healthcare (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Pamella de Barros MottaPost Graduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo 01525-000, SP, Brazil.
Marcela Leticia Leal GonçalvesPost Graduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo 01525-000, SP, Brazil.ORCID 0000-0003-1305-5257
Juliana Maria Altavista Sagretti GalloPost Graduation Program in Veterinary Medicine in the Coastal Environment, Universidade Metropolitana de Santos (UNIMES), Santos 11045-002, SP, Brazil.
Ana Paula Taboada SobralPost Graduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo 01525-000, SP, Brazil.ORCID 0000-0002-6846-6574
Lara Jansiski MottaPost Graduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo 01525-000, SP, Brazil.ORCID 0000-0002-7774-4345
Elaine Marcílio SantosPost Graduation Program in Health and Environment, Universidade Metropolitana de Santos (UNIMES), Santos 11045-002, SP, Brazil.
David José Casimiro de AndradeSchool of Dentistry, University of Porto, 4099-002 Porto, Portugal.
Cinthya Cosme Gutierrez DuranPost Graduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo 01525-000, SP, Brazil.
Kristianne Porta Santos FernandesPost Graduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo 01525-000, SP, Brazil.
Raquel Agnelli Mesquita-FerrariPost Graduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo 01525-000, SP, Brazil.
Anna Carolina Ratto Tempestini HorlianaPost Graduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo 01525-000, SP, Brazil.ORCID 0000-0003-3476-9064
Sandra Kalil BussadoriPost Graduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo 01525-000, SP, Brazil.

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001Fundação de Amparo à Pesquisa do Estado de São Paulo 2019/14229-6National Council for Scientific and Technological Development 306577/2020-8
6 · The paper itself

Abstract

backgroundTo compare photodynamic therapy and the use of probiotics in reducing halitosis assessed through gas chromatography and microbiome analysis.

methodsParticipants aged from 18 to 25 years showing sulfide (SH2) ≥ 112 ppb on gas chromatography were selected. They were divided into four treatment groups: Group 1-Tongue Scraping; Group 2-Antimicrobial Photodynamic Therapy (aPDT); Group 3-Probiotics; and Group 4-Antimicrobial Photodynamic Therapy (aPDT) and Probiotics. The halimetry process was performed before, immediately after the treatments, and 7 days, 14 days, and 30 days after the initial collection. The collections for later microbiological analysis were made along with the halimetry for microbiome analysis.

resultsTreatment with aPDT or probiotics under these experimental conditions was not able to change the bacteria present in the biofilm of the tongue.

conclusionsMore research is needed to know the behavior of the oral microbiome in the presence of halitosis and the effectiveness of new treatments.

Indexed as

antimicrobial photodynamic therapyhalitosismicrobiomeprobiotics

Identifiers

PMID38891198
PMCPMC11172044

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.