ArticleHealthcare (Basel, Switzerland)2024
Personality and Pain Outcomes in Rheumatic Disease: The Mediating Role of Psychological Flexibility.
Article in Healthcare (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neuroticism as a Common Factor in Depression and Anxiety Associated with Multiple Sclerosis-A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2024Pooled it
- Mental health-related quality of life mediates the association between psychosocial factors and medication adherence in rheumatoid arthritis.Clinical rheumatology · 2026Article
- Self-Esteem and Coping Modes as Mediators of the Social Support-Stigma Relationship in Rheumatoid Arthritis Patients: A Multicentre Cross-Sectional Study.Nursing open · 2026Article
- Article
- Personality traits have an effect on pain-related psychological variables in patients with chronic low back pain.PloS one · 2026Article
- The Path from Personality to Anxiety and Depression Is Mediated by Cognition in Multiple Sclerosis.Journal of personalized medicine · 2024Article
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Authors and funding
9 authors.
Funding
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Abstract
backgroundChronic pain is associated with increased disability and vulnerability to emotional disorders. Personality and psychological flexibility (PF) describe interindividual differences that shape the adjustment to chronic pain. Specifically, PF was found to be associated with pain, fatigue, anxiety, and depression intensity. Although previous studies established strong correlations between personality and pain outcomes, evidence on the nature of this relationship is scarce. Therefore, the objective of this study is to explore the mediating effect of PF on the relationship between personality and distress.
methodsThis transversal study included 108 participants (age M = 56.7, SD = 11.3) diagnosed with musculoskeletal chronic pain. Self-reported measures were administered by the medical care team. Multiple mediation models were performed for estimating the indirect effects on each outcome variable.
resultsAfter controlling for age and gender covariates, we found that PF completely mediated the relationship between personality traits and all pain outcomes and partially mediated the impact of extraversion on anxiety. In addition, emotional stability also had an indirect effect on anxiety through PF.
conclusionsPersonality traits and PF are significant predictors of pain outcomes. PF represents a core process mediating the impact of personality traits on the perceived intensity of pain, fatigue, anxiety, and depression in patients with rheumatic disease. These results could facilitate the application of individualized psychological interventions in clinical contexts targeting the reduction of emotional avoidance and in chronic pain patients.
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