Evidence map›Paper›PMID 38891042›Full record

ReviewCells2024

From Marrow to Bone and Fat: Exploring the Multifaceted Roles of Leptin Receptor Positive Bone Marrow Mesenchymal Stromal Cells.

Parash Prasad, Jose A Cancelas

Abstract readReview
In one paragraph

Review in Cells, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Cellular crosstalk in the bone marrow niche.Journal of translational medicine · 2024
    Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Parash PrasadDana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
Jose A CancelasDana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.

Funding

Novel Strategies to Improve Blood Transfusion PracticeP01HL158688 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Hongbo R Luo · 2022 to 2026
$12.9M
Mitochondria mediated intercellular metabolic coupling in bone marrow regenerationR01DK124115 · NIDDK · DANA-FARBER CANCER INST · PI Jose A. Cancelas · 2020 to 2026
$1.9M
NHLBI NIH HHS P01 HL158688NIDDK NIH HHS R01 DK124115NIH HHS R01DK124115
6 · The paper itself

Abstract

The bone marrow (BM) stromal cell microenvironment contains non-hematopoietic stromal cells called mesenchymal stromal cells (MSCs). MSCs are plastic adherent, form CFU-Fs, and give rise to osteogenic, adipogenic, chondrogenic progenitors, and most importantly provide HSC niche factor chemokine C-X-C motif ligand 12 (CXCL12) and stem cell factor (SCF). Different authors have defined different markers for mouse MSC identification like PDGFR

Indexed as

Mesenchymal Stem CellsReceptors, LeptinAnimalsBone and BonesBone MarrowBone Marrow CellsCell DifferentiationHematopoiesisHumansReceptors, Leptinadipogenesisbone marrowhematopoiesisleptin receptormesenchymal stromal cellsosteogenesis

Identifiers

PMID38891042
PMCPMC11171870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.