Evidence map›Paper›PMID 38890838›Full record

ArticleFoods (Basel, Switzerland)2024

Antibody Production and Immunoassay Development for Authenticating Chlorpheniramine Maleate Adulteration in Herbal Tea.

Jianhao Lin, Zhiwei Liu, Tian Guan, Yi Lei, Liangwen Pan, Xiaoqin Yu, Shiwei Zhang, Xin-An Huang, Hongtao Lei, Jiahong Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Foods (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jianhao LinGuangdong Provincial Key Laboratory of Food Quality and Safety/Nation-Local Joint Engineering Research Center for Machining and Safety of Livestock and Poultry Products, South China Agricultural University, Guangzhou 510642, China.ORCID 0009-0001-5648-6682
Zhiwei LiuGuangdong Provincial Key Laboratory of Food Quality and Safety/Nation-Local Joint Engineering Research Center for Machining and Safety of Livestock and Poultry Products, South China Agricultural University, Guangzhou 510642, China.
Tian GuanGuangdong Provincial Key Laboratory of Food Quality and Safety/Nation-Local Joint Engineering Research Center for Machining and Safety of Livestock and Poultry Products, South China Agricultural University, Guangzhou 510642, China.
Yi LeiGuangzhou Institute of Food Inspection, Guangzhou 511410, China.
Liangwen PanAnimal, Plant and Food Inspection and Quarantine Technology Center, Shanghai Customs, Shanghai 200135, China.
Xiaoqin YuSichuan Institute of Food Inspection, Chengdu 610097, China.
Shiwei ZhangNational Nutrition Food Testing Center, Shenzhen Academy of Metrology and Quality Inspection, Shenzhen 518131, China.
Xin-An HuangTropical Medicine Institute & South China Chinese Medicine Collaborative Innovation Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.ORCID 0000-0003-1628-7416
Hongtao LeiGuangdong Provincial Key Laboratory of Food Quality and Safety/Nation-Local Joint Engineering Research Center for Machining and Safety of Livestock and Poultry Products, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0002-1697-1747
Jiahong ChenGuangdong Provincial Key Laboratory of Food Quality and Safety/Nation-Local Joint Engineering Research Center for Machining and Safety of Livestock and Poultry Products, South China Agricultural University, Guangzhou 510642, China.ORCID 0000-0001-5607-2132

Funding

Generic Technique Innovation Team Construction of Modern Agriculture of Guangdong Province 2023KJ130Guangdong Marine Economic Development Program for Six Categories of Marine Industries no. GDNRC[2023]36Guangdong Natural Science Foundation 2023A1515011834National Key Research and Development Program of China 2023YFF1105103, 2023YFF1104200, 2023YFF1104700Zhongshan Science and Technology Innovation Team no. CXTD2022004
6 · The paper itself

Abstract

Chlorphenamine maleate is a prohibited additive found in herbal teas and health foods. Excessive intake of this substance can result in adverse health effects. In this study, two novel haptens, PEM and bepotastine (PB1), mimicking chlorphenamine maleate structure were designed and synthesized based on molecular simulation for developing two corresponding polyclonal antibodies (PEM-Ab and PB1-Ab), respectively. Afterward, an indirect competitive enzyme-linked immunosorbent assay (ic-ELISA) was developed to quickly and accurately detect chlorphenamine maleate in herbal teas using PB1-Ab, which has a high sensitivity and specificity. For chlorphenamine maleate, the half-maximal inhibitory concentration (IC

Indexed as

adulterationchlorphenamine maleateherbal teasmolecular simulation

Identifiers

PMID38890838
PMCPMC11172221

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.