Effects of exercise training on cardiac output in subjects with heart failure with preserved ejection fraction (HFpEF) - a protocol for a systematic review and meta-analysis.

Raphael Schoch, Benedikt Gasser, Philippe Beck, Christian Appenzeller-Herzog, Arno Schmidt-Trucksäss

Abstract read

In one paragraph

Article in Systematic reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Raphael Schoch *Department of Sport, Exercise and Health, Division of Sport and Exercise Medicine, University of Basel, Grosse Allee 6, 4052, Basel, Switzerland.

Benedikt Gasser *Department of Sport, Exercise and Health, Division of Sport and Exercise Medicine, University of Basel, Grosse Allee 6, 4052, Basel, Switzerland.

Philippe BeckDepartment of Sport, Exercise and Health, Division of Sport and Exercise Medicine, University of Basel, Grosse Allee 6, 4052, Basel, Switzerland.

Christian Appenzeller-HerzogUniversity Medical Library, University of Basel, 4051, Basel, Switzerland.

Arno Schmidt-TrucksässDepartment of Sport, Exercise and Health, Division of Sport and Exercise Medicine, University of Basel, Grosse Allee 6, 4052, Basel, Switzerland. arno.schmidt-trucksaess@unibas.ch.ORCID 0000-0002-4662-3911

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung 185217

6 · The paper itself

Abstract

backgroundPatients with heart failure with preserved ejection fraction (HFpEF) commonly experience exercise intolerance, resulting in reduced cardiorespiratory fitness. This is characterised by a decreased maximal oxygen uptake (V̇O

methodsWe will systematically search for literature describing the effects of supervised exercise training on CO in patients with HFpEF. All eligible studies published before 30 June 2023 in the following electronic databases will be included: MEDLINE (Ovid), Embase (Ovid), SPORTDiscus (EBSCOhost), and CENTRAL (Cochrane Library). Effect sizes will be extracted for CO before and after a supervised exercise training intervention at rest and maximal exercise. Mass of heterogeneity (I DISCUSSION: While several studies have reported a positive effect of supervised exercise training on cardiorespiratory fitness, attempts to assess the underlying determinants of V̇O SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42022361485.

Indexed as

Cardiac OutputExercise TherapyHeart FailureMeta-Analysis as TopicStroke VolumeSystematic Reviews as TopicCardiorespiratory FitnessExercise ToleranceHumansOxygen ConsumptionCardiac output (CO)ExerciseHeart failure with preserved ejection fraction (HFpEF)Meta-analysisSystematic review

Identifiers

PMID38890755

DOI10.1186/s13643-024-02529-w

PMCPMC11186211

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