Evidence map›Paper›PMID 38890674›Full record

ArticleBMC endocrine disorders2024

Central obesity may affect bone development in adolescents: association between abdominal obesity index ABSI and adolescent bone mineral density.

Rubing Lin, Yuao Tao, Chuang Li, Feifei Li, Zijian Li, Xingyu Hong, Yantong Liu

Abstract read
In one paragraph

Article in BMC endocrine disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Xiehuang San Extract Attenuates Insulin Resistance in Obese Rats via Gut Microbiota Modulation: Experimental Evidence.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  5. Article
  6. Article
  7. Effects of stress on bone health in children.Frontiers in endocrinology · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rubing Lin *Department of Orthopedics, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
Yuao Tao *Department of Spine Center, Medical School, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, China.
Chuang LiDepartment of Biological Sciences, Purdue University, West Lafayette, USA.
Feifei LiMolecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, USA.
Zijian LiMedical School of Chinese PLA, Beijing, China.
Xingyu HongHealth Service Center of Baiyun Street, Jiaojiang District, Zhejiang, 318000, China. 404343631@qq.com.
Yantong LiuDepartment of Computer Information Engineering, Kunsan National University, Gunsan, 54150, South Korea. lyt1994@kunsan.ac.kr.

Funding

Guangdong High-level Hospital Construction Fund and Sanming Project of Medicine in Shenzhen SZSM202011012
6 · The paper itself

Abstract

purposePrevious studies have suggested that obesity defined by body mass index(BMI) is a protective factor for bone mineral density(BMD), but have overlooked the potential influence of different types of obesity. This study aims to evaluate the correlation between abdominal obesity index A Body Shape Index(ABSI) and adolescent bone density, and analyze the relationship between abdominal obesity and bone metabolism.

methodsA total of 1557 adolescent participants were included in NHANES from 2007 to 2018. Calculate the ABSI using a specific formula that takes into account waist circumference and BMI. A weighted multiple linear regression model is used to evaluate the linear correlation between ABSI and BMD. Forest plots are used to analyze the correlations between subgroups, and cubic splines are limited to evaluate the nonlinear correlations and saturation effects between ABSI and BMD.

resultsAfter adjusting for confounding factors, there was a significant linear correlation (P < 0.01) between ABSI and femoral BMD, both as a continuous variable and an ordered categorical variable. The restrictive cubic spline curve indicates a significant nonlinear correlation and saturation effect between adolescent ABSI and BMD.

conclusionResearch has shown a significant negative correlation between ABSI and BMD at the four detection sites of the femur, and this correlation may vary slightly due to age, race, family income, and different detection sites. The research results indicate that compared to overall body weight, fat distribution and content may be more closely related to bone metabolism.

Indexed as

Body Mass IndexBone DensityBone DevelopmentNutrition SurveysObesity, AbdominalAdolescentChildCross-Sectional StudiesFemaleHumansMalePrognosisWaist CircumferenceAbdominal obesityA body shape indexBone mineral densityOsteoporosis

Identifiers

PMID38890674
PMCPMC11186089

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.