Evidence map›Paper›PMID 38890600›Full record

ArticleBMC nephrology2024

A very complicated UTI: malakoplakia following E. coli urinary tract infection.

Ayotola Fatola, Benjamin C Johnson, Laura Walsh, Diana Fang, Marissa J White, Dustin Le, Mohamed G Atta, C John Sperati, David N Hager

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ayotola FatolaDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. afatola1@jhmi.edu.
Benjamin C JohnsonDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Laura WalshDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Diana FangDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Marissa J WhiteDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Dustin LeDepartment of Medicine, Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Mohamed G AttaDepartment of Medicine, Division of Nephrology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
C John SperatiDepartment of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
David N HagerDepartment of Medicine, Division of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malakoplakia is a rare inflammatory disorder believed to result from a defect in macrophage phagocytic function triggering a granulomatous reaction. It can present with genitourinary, gastrointestinal, or cutaneous manifestations in immunocompromised or, less commonly, immunocompetent hosts. We describe a case of renal malakoplakia in a young, otherwise healthy patient presenting with nephromegaly and sepsis following an E. coli urinary tract infection. We discuss diagnosis and management, including antibiotic selection and the decision to pursue nephrectomy. This case highlights the potential for kidney recovery with prolonged antibiotic therapy in conjunction with adjunct immunomodulatory therapies and source control.

Indexed as

Escherichia coli InfectionsMalacoplakiaUrinary Tract InfectionsAdultAnti-Bacterial AgentsEscherichia coliHumansAnti-Bacterial AgentsE. coli UTIMalakoplakiaMichaelis-gutmann bodies

Identifiers

PMID38890600
PMCPMC11186150

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.