Evidence map›Paper›PMID 38890514›Full record

ArticleInternational journal of impotence research2025

Comparative outcomes of partial versus total penectomy for penile carcinoma: A retrospective cohort study on demographics and postoperative complications.

David A Velasquez, Allison Liu, Senthooran Kalidoss, Clinton Yeaman, Darren Bryk, Judy N Fustok, Thomas M Shelton, Hasan Alhameedi, Nalin Payakachat, Mohamed Kamel and 4 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in International journal of impotence research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

David A VelasquezUniversity of Chicago, Department of Surgery, Section of Urology, Chicago, IL, USA.ORCID http://orcid.org/0009-0003-0475-4918
Allison LiuUniversity of Chicago, Department of Surgery, Section of Urology, Chicago, IL, USA.
Senthooran KalidossUniversity of Chicago, Department of Surgery, Section of Urology, Chicago, IL, USA.
Clinton YeamanUniversity of Virginia, Department of Urology, Charlottesville, VA, USA.
Darren BrykUniversity of Virginia, Department of Urology, Charlottesville, VA, USA.
Judy N FustokJohns Hopkins University, Department of Radiology, Baltimore, MD, USA.ORCID http://orcid.org/0000-0002-6190-2409
Thomas M SheltonUniversity of Indiana, Department of Urology, Indianapolis, IN, USA.
Hasan AlhameediUniversity of Virginia, Department of Urology, Charlottesville, VA, USA.
Nalin PayakachatUniversity of Arkansas, Division of Pharmaceutical Evaluation and Policy, Arkansas, AR, USA.
Mohamed KamelUniversity of Arkansas, Division of Pharmaceutical Evaluation and Policy, Arkansas, AR, USA.
Braian R LedesmaDesai Sethi Urology Institute University of Miami, Department of Urology, Miami, FL, USA.ORCID http://orcid.org/0000-0003-1091-5493
Mahmoud I KhalilUniversity of Chicago, Department of Surgery, Section of Urology, Chicago, IL, USA.
Ryan SmithUniversity of Virginia, Department of Urology, Charlottesville, VA, USA.
Omer RaheemUniversity of Chicago, Department of Surgery, Section of Urology, Chicago, IL, USA. oraheem@bsd.uchicago.edu.ORCID http://orcid.org/0000-0001-6117-116X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When feasible from an oncologic standpoint, partial penectomy (PP) is often preferred to total penectomy (TP) for penile cancer treatment, for the preservation of functional urinary outcomes. However, to date, there has not been a direct comparison of perioperative outcomes between PP and TP. Comparing treatments for penile cancer has proven difficult due to the rarity of penile cancer in the United States. We aimed to report differences in pre-operative risk factors, intra-operative outcomes, and postoperative outcomes between TP and PP for penile cancer. Using the National Surgical Quality Improvement Program database, we conducted a retrospective cohort review of penile cancer patients enlisted in the database between the years 2006-2016 using the International Classification of Diseases clinical modification 9th revision codes. A total of 260 patients, 67 TP and 193 PP patients, were included. PP patients were less likely to be transferred patients (p = 0.002), diabetic (p = 0.026), and were more likely to have preoperative laboratory values within normal limits. PP patients also had shorter lengths of stay in the hospital (p < 0.001) and operating time (p < 0.001). Significant differences were also found for inpatient stay (p < 0.001), 30-day post-surgery complications (p < 0.001), deep incisional surgical site infection (SSI) (p = 0.017), wound disruption (p = 0.017), intraoperative or postoperative transfusion (p = 0.029), and sepsis (p < 0.005). Finally, PP patients required fewer concurrent surgical procedures (p < 0.001). Demographic differences between PP and TP patients may reflect patients presenting with more advanced oncologic disease. PP is associated with fewer postoperative complications, shorter surgeries, shorter hospital stays, fewer concurrent surgical procedures, and comorbid conditions compared to TP. A gap remains in the reported data pertaining to postoperative sexual function and erectile outcomes for PP at a national level.

Indexed as

Penile NeoplasmsPenisPostoperative ComplicationsUrologic Surgical Procedures, MaleAdultAgedHumansLength of StayMaleMiddle AgedOperative TimeRetrospective StudiesRisk FactorsTreatment Outcome

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.