Evidence map›Paper›PMID 38889926›Full record

ArticleRespiratory care2024

Invasive Mechanical Ventilation and Risk of Hospital-Acquired Venous Thromboembolism.

Elizabeth E Havlicek, Jamie Palumbo, Gerardo Soto-Campos, Neil A Goldenberg, Anthony A Sochet

Abstract read
In one paragraph

Article in Respiratory care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Hospital-Acquired Venous Thromboembolism Among Children With Tracheostomy: A North American Virtual Pediatric Systems Registry Study, 2016-2023.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Elizabeth E HavlicekDepartment of Pediatrics, University of South Florida Morsani College of Medicine, Tampa, Florida.
Jamie PalumboVirtual Pediatric Systems, LLC, Division of Analytics, Los Angeles, California.
Gerardo Soto-CamposVirtual Pediatric Systems, LLC, Division of Analytics, Los Angeles, California.
Neil A GoldenbergDepartment of Medicine and Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland; and Johns Hopkins Institute for Clinical and Translational Research, St. Petersburg, Florida.
Anthony A SochetDepartment of Anesthesia and Critical Care Medicine, Johns Hopkins All Children's Hospital, St. Petersburg, Florida. Anthony.Sochet@jhmi.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study sought to estimate the overall cumulative incidence and odds of Hospital-acquired venous thromboembolism (VTE) among critically ill children with and without exposure to invasive ventilation. In doing so, we also aimed to describe the temporal relationship between invasive ventilation and hospital-acquired VTE development.

methodsWe performed a retrospective cohort study using Virtual Pediatric Systems (VPS) data from 142 North American pediatric ICUs among children < 18 y of age from January 1, 2016-December 31, 2022. After exclusion criteria were applied, cohorts were identified by presence of invasive ventilation exposure. The primary outcome was cumulative incidence of hospital-acquired VTE, defined as limb/neck deep venous thrombosis or pulmonary embolism. Multivariate logistic regression was used to determine whether invasive ventilation was an independent risk factor for hospital-acquired VTE development.

resultsOf 691,118 children studied, 86,922 (12.4%) underwent invasive ventilation. The cumulative incidence of hospital-acquired VTE for those who received invasive ventilation was 1.9% and 0.12% for those who did not (

conclusionsIn this multi-center retrospective review from the VPS registry, invasive ventilation exposure and duration were independent risk factors for hospital-acquired VTE among critically ill children. Children undergoing invasive ventilation represent an important target population for risk-stratified thromboprophylaxis trials.

Indexed as

Respiration, ArtificialVenous ThromboembolismAdolescentChildChild, PreschoolCritical IllnessFemaleHumansIncidenceInfantIntensive Care Units, PediatricIntubation, IntratrachealLogistic ModelsMaleRetrospective StudiesRisk Factorshospital-acquired venous thromboembolisminvasive ventilationpediatric critical care medicinepediatrics

Identifiers

PMID38889926
PMCPMC11549620

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.