Evidence map›Paper›PMID 38888862›Full record

ArticleAnnals of surgical oncology2024

Unveiling Melanoma: A Deep Dive into Disparities at a Latin-American Cancer Institute.

Gonzalo Ziegler-Rodriguez, Gabriel De La Cruz-Ku, Luis Piedra-Delgado, Jorge Torres-Maldonado, Jorge Dunstan, Jose Manuel Cotrina-Concha, Jose Antonio Galarreta-Zegarra, Gabriela Calderon-Valencia, Sheila Vilchez-Santillan, Miguel Pinillos-Portella and 1 more

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In one paragraph

Article in Annals of surgical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Lymphatic Complications in Patients Undergoing Melanoma Surgery in Peru.Plastic and reconstructive surgery. Global open · 2026
    Article
  2. Multidisciplinary Management of Palpebral Melanoma.Plastic and reconstructive surgery. Global open · 2025
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Gonzalo Ziegler-RodriguezInstituto Nacional de Enfermedades Neoplasicas, Lima, Peru. gonzaloziegler@gmail.com.ORCID http://orcid.org/0000-0002-8486-8477
Gabriel De La Cruz-KuUniversidad Cientifica del Sur, Lima, Peru.
Luis Piedra-DelgadoUniversidad Cientifica del Sur, Lima, Peru.
Jorge Torres-MaldonadoInstituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Jorge DunstanInstituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Jose Manuel Cotrina-ConchaInstituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Jose Antonio Galarreta-ZegarraInstituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Gabriela Calderon-ValenciaInstituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Sheila Vilchez-SantillanInstituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Miguel Pinillos-PortellaInstituto Nacional de Enfermedades Neoplasicas, Lima, Peru.
Mecker G MöllerDivision of Surgical Oncology, Department of Surgery, University of Chicago Pritzker School of Medicine, Chicago, IL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe worldwide incidence of melanoma has increased in the last 40 years. Our aim was to describe the clinic-pathological characteristics and outcomes of three cohorts of patients diagnosed with melanoma in a Latin-American cancer institute during the last 20 years.

methodsWe evaluated three retrospective patient cohorts diagnosed with melanoma at Instituto Nacional de Enfermedades Neoplasicas (INEN), a public hospital in Lima, Peru, for the years 2005-2006, 2010-2011, and 2017-2018. Survival rate differences were assessed using the Log-rank test.

resultsOverall, 584 patients were included (only trunk and extremities); 51% were male, the mean age was 61 (3-97) years, and 48% of patients resided in rural areas. The mean time to diagnosis was 22.6 months, and the mean Breslow thickness was 7.4 mm (T4). Lower extremity was the most common location (72%). A majority of the patients (55%) had metastases at the time of presentation, with 36% in stage III and 19% in stage IV. Cohorts were distributed as 2005-2006 (n = 171), 2010-2011 (n = 223), and 2017-2018 (n = 190). No immunotherapy was used. Cohort C exhibited the most significant increase in stage IV diagnoses (12.3%, 15.7%, 28.4%, respectively; p < 0.01). The median overall survival rates at the three-year follow-up demonstrated a decline over the years for stages II (97%, 98%, 57%, respectively; p < 0.05) and III (66%, 77%, 37%; p < 0.01).

conclusionsThere has been a worsening in the incidence of late-stage metastatic melanoma in Peru throughout the years, coupled with a significant decline in overall survival rates. This is underscored by the fact that half of the population lives in regions devoid of oncological access.

Indexed as

MelanomaSkin NeoplasmsAdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleFollow-Up StudiesHealthcare DisparitiesHumansIncidenceLatin AmericaMaleMiddle AgedDisparitiesLatin-AmericanMelanomaSkin

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.