Evidence map›Paper›PMID 38888739›Full record

ArticleAbdominal radiology (New York)2024

Comparison of intra- and inter-reader agreement of abbreviated versus comprehensive MRCP for pancreatic cyst surveillance.

Chenchan Huang, Vinay Prabhu, Paul Smereka, Abhinav Vij, Rebecca Anthopolos, Cristina H Hajdu, Bari Dane

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Abdominal radiology (New York), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chenchan HuangNYU Langone Health, 660 First Avenue, 3rd floor, New York, NY, 10016, USA. Chenchan.huang@nyulangone.org.ORCID 0000-0002-9530-1206
Vinay PrabhuNYU Langone Health, 660 First Avenue, 3rd floor, New York, NY, 10016, USA.
Paul SmerekaNYU Langone Health, 660 First Avenue, 3rd floor, New York, NY, 10016, USA.
Abhinav VijNYU Langone Health, 660 First Avenue, 3rd floor, New York, NY, 10016, USA.
Rebecca AnthopolosBiostatistics Division within Department of Population Health, NYU Grossman School of Medicine, New York, United States.
Cristina H HajduNYU Langone Health, 660 First Avenue, 3rd floor, New York, NY, 10016, USA.
Bari DaneNYU Langone Health, 660 First Avenue, 3rd floor, New York, NY, 10016, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo retrospectively compare inter- and intra-reader agreement of abbreviated MRCP (aMRCP) with comprehensive MRI (cMRCP) protocol for detection of worrisome features, high-risk stigmata, and concomitant pancreatic cancer in pancreatic cyst surveillance.

methods151 patients (104 women, mean age: 69[10] years) with baseline and follow-up contrast-enhanced MRIs were included. This comprised 138 patients under cyst surveillance with 5-year follow-up showing no pancreatic ductal adenocarcinoma (PDAC), 6 with pancreatic cystic lesion-derived malignancy, and 7 with concomitant PDAC. The aMRCP protocol used four sequences (axial and coronal Half-Fourier Single-shot Turbo-spin-Echo, axial T1 fat-saturated pre-contrast, and 3D-MRCP), while cMRCP included all standard sequences, including post-contrast. Three blinded abdominal radiologists assessed baseline cyst characteristics, worrisome features, high-risk stigmata, and PDAC signs using both aMRCP and cMRCP, with a 2-week washout period. Intra- and inter-reader agreement were calculated using Fleiss' multi-rater kappa and Intra-class Correlation Coefficient (ICC). 95% confidence intervals (CI) were calculated.

resultsCyst size, growth, and abrupt main pancreatic duct transition had strong intra- and inter-reader agreement. Intra-reader agreement was ICC = 0.93-0.99 for cyst size, ICC = 0.71-1.00 for cyst growth, and kappa = 0.83-1.00 for abrupt duct transition. Inter-reader agreement for cyst size was ICC = 0.86 (aMRCP) and ICC = 0.83 (cMRCP), and for abrupt duct transition was kappa = 0.84 (aMRCP) and kappa = 0.69 (cMRCP). Thickened cyst wall, mural nodule and cyst-duct communication demonstrated varying intra-reader agreements and poor inter-reader agreements.

conclusionaMRCP showed high intra- and inter-reader agreement for most pancreatic cyst parameters that highly rely on T2-weighted sequences.

Indexed as

Cholangiopancreatography, Magnetic ResonancePancreatic CystPancreatic NeoplasmsAgedContrast MediaFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedObserver VariationPancreasReproducibility of ResultsRetrospective StudiesContrast MediaAbbreviated MRCPBranch-duct IPMNMRCP surveillancePancreatic cyst

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.