Infections and gender: clues for diagnosis of adrenal insufficiency-a case report and a review of the literature.

Giacomo Grandi, Michele Di Stefano, Chiara Cebrelli, Caterina Mengoli, Antonio Di Sabatino

Abstract readCase ReportsReview

In one paragraph

Review in Internal and emergency medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Giacomo GrandiDepartment of Internal Medicine, IRCCS San Matteo Hospital Foundation, University of Pavia, P.le Camillo Golgi 2, 27100, Pavia, Italy.ORCID 0000-0003-1795-7645

Michele Di StefanoDepartment of Internal Medicine, IRCCS San Matteo Hospital Foundation, University of Pavia, P.le Camillo Golgi 2, 27100, Pavia, Italy.

Chiara CebrelliDepartment of Internal Medicine, IRCCS San Matteo Hospital Foundation, University of Pavia, P.le Camillo Golgi 2, 27100, Pavia, Italy.

Caterina MengoliDepartment of Internal Medicine, IRCCS San Matteo Hospital Foundation, University of Pavia, P.le Camillo Golgi 2, 27100, Pavia, Italy.

Antonio Di SabatinoDepartment of Internal Medicine, IRCCS San Matteo Hospital Foundation, University of Pavia, P.le Camillo Golgi 2, 27100, Pavia, Italy. a.disabatino@smatteo.pv.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The clinical presentation of adrenal insufficiency, a condition causing adrenal hormone deficiency, is characterised by non-specific symptoms and signs: consequently, an important diagnostic delay is often evident which correlates with an increased mortality. This case report shows how the clustering of some symptoms and signs may hamper the diagnostic suspicion for this condition: serum electrolyte alterations and weight loss, when associated to recurrent infections and, in female patients, an empty sella may further guide the clinician towards a diagnosis of adrenal insufficiency. Accordingly, a clinical approach taking into account gender medicine could improve the diagnostic workup.

Indexed as

Adrenal InsufficiencyFemaleHumansInfectionsMaleMiddle AgedSex FactorsAdrenal insufficiencyEmpty sella syndromeGender medicineInfection

Identifiers

PMID38888722

DOI10.1007/s11739-024-03613-8

PMCPMC11466904

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