Evidence map›Paper›PMID 38887953›Full record

Trial reportCirculation. Cardiovascular quality and outcomes2024

Text Messages to Promote Physical Activity in Patients With Cardiovascular Disease: A Micro-Randomized Trial of a Just-In-Time Adaptive Intervention.

Jessica R Golbus, Jieru Shi, Kashvi Gupta, Rachel Stevens, V Swetha E Jeganathan, Evan Luff, Thomas Boyden, Bhramar Mukherjee, Sarah Kohnstamm, Vlad Taralunga and 7 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Circulation. Cardiovascular quality and outcomes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04587882 (Virtual AppLication-supported ENvironment To INcrease Exercise During Cardiac Rehabilitation Study), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04587882 nacompletednot on this map

Virtual AppLication-supported ENvironment To INcrease Exercise During Cardiac Rehabilitation Study

TypeinterventionalSponsorUniversity of MichiganRan2020 to 2022Enrolled223ConditionsHeart Diseases, Cardiovascular DiseasesArmsTelehealth, Control
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. "It felt more real": Investigating the User Experience of the MiWaves Personalizing JITAI Pilot Study.International Conference on Pervasive Computing Technologies for Healthcare : [proceedings]. International Conference on Pervasive Computing Technologies for Healthcare · 2026
    Article
  8. Development of a Health Text Message System to Support Stroke Prevention: A Component of the Love Your Brain Digital Platform.Health expectations : an international journal of public participation in health care and health policy · 2025
    Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Jessica R GolbusDivision of Cardiovascular Diseases, Department of Internal Medicine (J.R.G., R.S., V.S.E.J., E.L., S. Kohnstamm, B.K.N.), University of Michigan.
Jieru ShiDepartment of Biostatistics, University of Michigan School of Public Health, Ann Arbor (J.S., W.D.).ORCID 0000-0003-1108-1558
Kashvi GuptaDepartment of Internal Medicine, University of Missouri Kansas City (K.G.).
Rachel StevensDivision of Cardiovascular Diseases, Department of Internal Medicine (J.R.G., R.S., V.S.E.J., E.L., S. Kohnstamm, B.K.N.), University of Michigan.
V Swetha E JeganathanDivision of Cardiovascular Diseases, Department of Internal Medicine (J.R.G., R.S., V.S.E.J., E.L., S. Kohnstamm, B.K.N.), University of Michigan.
Evan LuffDivision of Cardiovascular Diseases, Department of Internal Medicine (J.R.G., R.S., V.S.E.J., E.L., S. Kohnstamm, B.K.N.), University of Michigan.
Thomas BoydenDivision of Cardiovascular Diseases, Department of Internal Medicine, Spectrum Health, MI (T.B.).
Bhramar MukherjeeSchool of Public Health (B.M., K.R.), University of Michigan.ORCID 0000-0003-0118-4561
Sarah KohnstammDivision of Cardiovascular Diseases, Department of Internal Medicine (J.R.G., R.S., V.S.E.J., E.L., S. Kohnstamm, B.K.N.), University of Michigan.
Vlad TaralungaCareEvolution, Ann Arbor, MI (V.T., V.K.).ORCID 0009-0004-0555-8967
Vik KheterpalCareEvolution, Ann Arbor, MI (V.T., V.K.).
Sachin KheterpalDepartment of Anesthesiology (S. Kheterpal), University of Michigan.ORCID 0000-0002-6546-0273
Kenneth ResnicowSchool of Public Health (B.M., K.R.), University of Michigan.ORCID 0000-0003-1416-9627
Susan MurphyDepartments of Statistics & Computer Science, Harvard University, Boston, MA (S.M.).ORCID 0000-0002-2032-4286
Walter DempseyDepartment of Biostatistics, University of Michigan School of Public Health, Ann Arbor (J.S., W.D.).ORCID 0000-0002-6510-4121
Predrag KlasnjaSchool of Information (P.K.), University of Michigan.ORCID 0000-0002-4570-703X
Brahmajee K NallamothuDivision of Cardiovascular Diseases, Department of Internal Medicine (J.R.G., R.S., V.S.E.J., E.L., S. Kohnstamm, B.K.N.), University of Michigan.ORCID 0000-0003-4331-6649

Funding

Pilot and Mentoring CoreP50DA054039 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Inbal Billie Nahum-Shani · 2021 to 2026
$18.2M
MObile health interVention to INcrease activity in Heart Failure (MOVIN-HF)K23HL168220 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Rachel Golbus · 2023 to 2026
$730k
NHLBI NIH HHS K23 HL168220NHLBI NIH HHS L30 HL143700NIDA NIH HHS P50 DA054039
6 · The paper itself

Abstract

backgroundText messages may enhance physical activity levels in patients with cardiovascular disease, including those enrolled in cardiac rehabilitation. However, the independent and long-term effects of text messages remain uncertain.

methodsThe VALENTINE study (Virtual Application-supported Environment to Increase Exercise) was a micro-randomized trial that delivered text messages through a smartwatch (Apple Watch or Fitbit Versa) to participants initiating cardiac rehabilitation. Participants were randomized 4× per day over 6-months to receive no text message or a message encouraging low-level physical activity. Text messages were tailored on contextual factors (eg, weather). Our primary outcome was step count 60 minutes following a text message, and we used a centered and weighted least squares mean method to estimate causal effects. Given potential measurement differences between devices determined a priori, data were assessed separately for Apple Watch and Fitbit Versa users over 3 time periods corresponding to the initiation (0-30 days), maintenance (31-120 days), and completion (121-182 days) of cardiac rehabilitation.

resultsOne hundred eight participants were included with 70 552 randomizations over 6 months; mean age was 59.5 (SD, 10.7) years with 36 (32.4%) female and 68 (63.0%) Apple Watch participants. For Apple Watch participants, text messages led to a trend in increased step count by 10% in the 60-minutes following a message during days 1 to 30 (95% CI, -1% to +20%), with no effect from days 31 to 120 (+1% [95% CI, -4% to +5%]), and a significant 6% increase during days 121 to 182 (95% CI, +0% to +11%). For Fitbit users, text messages significantly increased step count by 17% (95% CI, +7% to +28%) in the 60-minutes following a message in the first 30 days of the study with no effect subsequently.

conclusionsIn patients undergoing cardiac rehabilitation, contextually tailored text messages may increase physical activity, but this effect varies over time and by device. REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT04587882.

Indexed as

Cardiac RehabilitationCardiovascular DiseasesExerciseText MessagingActigraphyAgedFemaleFitness TrackersHumansMaleMiddle AgedTime FactorsTreatment Outcomecardiac rehabilitationcardiovascular diseasesexercisetext messaging

Identifiers

PMID38887953
PMCPMC11251861

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.