Evidence map›Paper›PMID 38887918›Full record

ArticleJournal of cachexia, sarcopenia and muscle2024

Comparison of the impact of longitudinal body mass index changes on cardiac arrest risk between normal and overweight populations.

Youn-Jung Kim, Min-Ju Kim, Ye-Jee Kim, Won Young Kim

Abstract read
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Article in Journal of cachexia, sarcopenia and muscle, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Youn-Jung KimDepartment of Emergency Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
Min-Ju KimDepartment of Clinical Epidemiology and Biostatistics, Asan Medical Center, Seoul, South Korea.
Ye-Jee KimDepartment of Clinical Epidemiology and Biostatistics, Asan Medical Center, Seoul, South Korea.
Won Young KimDepartment of Emergency Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.ORCID 0000-0002-6904-5966

Funding

Medical AI Co., Ltd
6 · The paper itself

Abstract

backgroundBeing overweight is a key modifiable risk factor for cardiovascular disease. However, the impact of longitudinal changes in body mass index (BMI) on the risk of out-of-hospital cardiac arrests (OHCA) remains unclear, especially among overweight populations.

methodsThis nested case-control study utilized data from the Korean National Health Information Database between 2009 and 2018. A total of 23 453 OHCA patients, who underwent national health check-ups within 1 and 2-4 years before OHCA occurrence, and 31 686 controls, who underwent similar national health check-ups, were included. The study population was matched for sex, age and survival status. Conditional logistic regression was employed to analyse the odds ratios (ORs) and 95% confidence intervals (CIs) of each BMI per cent change in assessing the risk of OHCA occurrence within 1 year.

resultsA reverse J-shaped association between BMI per cent change and OHCA risk was observed, even among overweight populations. Among the overweight populations, weight loss significantly increased OHCA risk, with ORs (95% CI) of 4.10 (3.23-5.20) for severe weight loss (BMI decrease > 15%), 2.72 (2.33-3.17) for moderate weight loss (BMI decrease 10-15%) and 1.46 (1.35-1.59) for mild weight loss (BMI decrease 5-10%). Conversely, mild weight gain (BMI increase 5-10%) did not significantly increase OHCA risk. The impact of weight changes on the occurrence of OHCA differed by sex, being more prominent in males.

conclusionsSignificant weight changes within a 4-year period increase the risk of OHCA with a reverse J-shaped association, even among overweight and obese individuals. Maintaining a stable weight could be a reliable public health strategy irrespective of the weight status, particularly for males.

Indexed as

Body Mass IndexOverweightAdultAgedCase-Control StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedOut-of-Hospital Cardiac ArrestRepublic of KoreaRisk Factorsbody mass indexbody weightobesityout‐of‐hospital cardiac arrestoverweight

Identifiers

PMID38887918
PMCPMC11294010

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.