Evidence map›Paper›PMID 38887845›Full record

ArticleJournal of the American Chemical Society2024

The Human Ganglioside Interactome in Live Cells Revealed Using Clickable Photoaffinity Ganglioside Probes.

Gao-Lan Zhang, Mitchell J Porter, Abduselam K Awol, Benjamin C Orsburn, Samuel W Canner, Jeffrey J Gray, Robert N O'Meally, Robert N Cole, Ronald L Schnaar

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Predictions from deep learning propose substantial protein-carbohydrate interplay.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Review
  3. Gangliosides in molecular interactions and cell regulation.The Journal of biological chemistry · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gao-Lan ZhangDepartment of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
Mitchell J PorterDepartment of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
Abduselam K AwolDepartment of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
Benjamin C OrsburnDepartment of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.ORCID 0000-0002-0774-3750
Samuel W CannerProgram in Molecular Biophysics, Johns Hopkins University, Baltimore, Maryland 21218, United States.ORCID 0000-0002-8678-0639
Jeffrey J GrayProgram in Molecular Biophysics, Johns Hopkins University, Baltimore, Maryland 21218, United States.ORCID 0000-0001-6380-2324
Robert N O'MeallyDepartment of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
Robert N ColeDepartment of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
Ronald L SchnaarDepartment of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.ORCID 0000-0002-7701-5484

Funding

Translational Research Central ServicesP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI ALAN KEITH MEEKER · 1985 to 2026
$208.6M
Prediction of the Structures of Protein ComplexesR35GM141881 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI JEFFREY J GRAY · 2021 to 2026
$7.6M
Program of Molecular BiophysicsT32GM135131 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Karen G. Fleming · 2020 to 2026
$5.4M
The Chemistry-Biology Interface Program at Johns Hopkins UniversityT32GM080189 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ROKITA, STEVEN E · 2008 to 2022
$3.5M
Ganglioside interactome toolkitU01CA241953 · NCI · JOHNS HOPKINS UNIVERSITY · PI SCHNAAR, RONALD L · 2019 to 2021
$1.5M
The Chemistry-Biology Interface Program at Johns Hopkins UniversityT32GM149382 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI STEVEN E ROKITA · 2023 to 2026
$1.4M
Zeiss LSM780 Confocal Microscope for a Core FacilityS10OD016374 · OD · JOHNS HOPKINS UNIVERSITY · PI KUO, SCOT CHARLES · 2013 to 2013
$584k
NCI NIH HHS P30 CA006973NCI NIH HHS U01 CA241953NIGMS NIH HHS R35 GM141881NIGMS NIH HHS T32 GM080189NIGMS NIH HHS T32 GM135131NIGMS NIH HHS T32 GM149382NIH HHS S10 OD016374
6 · The paper itself

Abstract

Gangliosides, sialic acid bearing glycosphingolipids, are components of the outer leaflet of plasma membranes of all vertebrate cells. They contribute to cell regulation by interacting with proteins in their own membranes (

Indexed as

Click ChemistryGangliosidesCell MembraneHumansMolecular ProbesPhotoaffinity LabelsGangliosidesMolecular ProbesPhotoaffinity Labels

Identifiers

PMID38887845
PMCPMC11650378

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.