SynthesisFrontiers in sports and active living2024
Effect of open vs. closed kinetic chain exercises in ACL rehabilitation on knee joint pain, laxity, extensor muscles strength, and function: a systematic review with meta-analysis.
Synthesis in Frontiers in sports and active living, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06797102 (Comparative Effects of Neuromuscular Training Vs Close Chain Exercises in Athletes With Post Operative ACL Injury), which is not on this map. Cited by 19 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparative Effects of Neuromuscular Training Vs Close Chain Exercises in Athletes With Post Operative ACL Injury
Who cites it
19 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Comparative effectiveness of resistance training modalities after anterior cruciate ligament reconstruction: a network meta-analysis of randomized controlled trials.Frontiers in physiology · 2026Pooled it
- Evaluating the effectiveness of preventive training programs in reducing the incidence of knee injuries: a systematic review and meta-analysis.Frontiers in public health · 2026Pooled it
- Preventive interventions on ACL injury reduction based on the landing error scoring system evaluation tool: a systematic review and network meta-analysis.BMC musculoskeletal disorders · 2025Pooled it
- The Efficacy of Closed Versus Open Kinetic Chain Exercise in Knee Osteoarthritis-A Systematic Review and Meta-Analysis.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2025Pooled it
- Effect of Knee Angle Specific (60°-90°) Combine versus Isolated Kinetic Chain on Post ACL Recovery Outcomes: A Randomized Control Trial.Journal of multidisciplinary healthcare · 2025Trial
- ACL rehabilitation after reconstruction: Evidence-based consensus recommendations from the German Knee Society-Part IV.Journal of experimental orthopaedics · 2026Article
- The Effects of External Lower Limb Weight or Pressure Application on Human Knee Joint Proprioception in Resting and Fatigue Conditions: A Randomized Trial.Journal of functional morphology and kinesiology · 2026Article
- Early-Phase Quadriceps Activation After Knee Surgery: A Narrative Review of Current Rehabilitation Interventions and Identification of an Unmet Clinical Need.Journal of clinical medicine · 2026Review
- Comparison of clinical efficacy between all-inside technique and traditional technique in anterior cruciate ligament reconstruction under knee arthroscopy.Journal of orthopaedic surgery and research · 2026Article
- Enhancing Knee Joint Proprioception in Healthy Adults Through Exergame Training With Augmented Feedback: Randomized Controlled Pilot Trial.JMIR rehabilitation and assistive technologies · 2026Article
- Combining motor competence and motor learning strategies helps to reduce the risk of biomechanical factors associated with ACL injury.BMC sports science, medicine & rehabilitation · 2026Article
- Advances in rehabilitation for bone and joint pain: a critical narrative review of evidence, gaps, and future directions.Frontiers in pain research (Lausanne, Switzerland) · 2026Review
- Rehabilitation guidelines after autograft anterior cruciate ligament reconstruction need more graft-specific exercise recommendations-A scoping review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Article
- Return To Sport Following ACL Reconstruction.Current reviews in musculoskeletal medicine · 2025Review
- Blood Flow Restriction Training Prior to and After Anterior Cruciate Ligament Reconstruction: A Scoping Review.Journal of functional morphology and kinesiology · 2025Review
- Optimizing return to sports after anterior cruciate ligament reconstruction: A multi-factorial umbrella review on rehabilitation strategies.Journal of clinical orthopaedics and trauma · 2025Review
- Innovative Rehabilitation of an Anterior Cruciate Ligament Tear in a Football Player: Muscle Chain Approach-A Case Study.Journal of clinical medicine · 2025Article
- Investigating the effects of closed kinetic chain exercises on joint position sense, functionality, range of motion, and pain in individuals with distal radius fracture: a randomized controlled trial.BMC sports science, medicine & rehabilitation · 2025Article
- Criteria-Based Decision Making for Introducing Open Kinetic Chain Exercise after-ACL Reconstruction: A Scoping Review.Sports medicine - open · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anterior cruciate ligament (ACL) injuries are common among physically active individuals, often requiring ACL reconstruction (ACLR) for recovery. Rehabilitating these injuries involves determining the appropriate timing for initiating open kinetic chain (OKC) exercises. Although OKC exercises are effective post-ACLR, their use in rehabilitation remains a subject of debate. Therefore, this study aims to conduct a systematic review to determine whether OKC or closed kinetic chain (CKC) exercises result in differences in laxity, strength of the knee extensor muscle group, function, and functional performance in ACL rehabilitation. Five electronic databases were searched for randomized controlled between-group trials (RCTs). Two reviewers independently evaluated the risk of bias using the PEDro scale. We performed a meta-analysis using a random-effects model or calculated mean differences (fixed-effect) where appropriate. Certainty of evidence was judged using the GRADE approach. The systematic literature search yielded 480 articles, of which 9 met the inclusion criteria. The evidence for all outcomes ranged from very low to low certainty. Across all comparisons, inconsistent results were found in outcome measures related to knee function between OKC and CKC exercises post-ACLR. A significant increase in quadriceps isokinetic strength was found in post-ACLR and ACL-deficient knees in favor of OKC exercises at 3 ( Systematic Review Registration: PROSPERO [CRD42023475230].
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.