Evidence map›Paper›PMID 38887645›Full record

ArticleRSC advances2024

Preparation of an injectable zinc-containing hydrogel with double dynamic bond and its potential application in the treatment of periodontitis.

Mei Yang, Dejiang Du, Yuanping Hao, Zhaojian Meng, Haiyu Zhang, Yuhan Liu

Abstract read
In one paragraph

Article in RSC advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mei YangQingdao Stomatological Hospital Affiliated to Qingdao University Qingdao 266000 Shandong China.
Dejiang DuQingdao Stomatological Hospital Affiliated to Qingdao University Qingdao 266000 Shandong China.
Yuanping HaoQingdao Stomatological Hospital Affiliated to Qingdao University Qingdao 266000 Shandong China.ORCID https://orcid.org/0000-0003-2930-2697
Zhaojian MengQingdao Stomatological Hospital Affiliated to Qingdao University Qingdao 266000 Shandong China.
Haiyu ZhangQingdao Stomatological Hospital Affiliated to Qingdao University Qingdao 266000 Shandong China.
Yuhan LiuQingdao Stomatological Hospital Affiliated to Qingdao University Qingdao 266000 Shandong China.ORCID https://orcid.org/0000-0003-0567-7275

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontal tissue regeneration continues to face significant clinical challenges. Periodontitis leads to alveolar bone resorption and even tooth loss due to persistent microbial infection and persistent inflammatory response. As a promising topical drug delivery system, the application of hydrogels in the controlled release of periodontal bioactive drugs has aroused great interest. Therefore, the design and preparation of an injectable hydrogel with self-repairing properties for periodontitis treatment is still in great demand. In this study, polysaccharide-based self-healing hydrogels with antimicrobial osteogenic properties were developed. Zinc ions are introduced into a dynamic cross-linking network formed by dynamic Schiff bases between carboxymethyl chitosan and oxidized hyaluronic acid

Identifiers

PMID38887645
PMCPMC11181151

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.