Evidence map›Paper›PMID 38887489›Full record

ReviewOpen forum infectious diseases2024

Epidemiology, Clinical Manifestations, and Outcome of Mucormycosis in Solid Organ Transplant Recipients: A Systematic Review of Reported Cases.

Emanuele Palomba, Marta Colaneri, Cecilia Azzarà, Marco Fava, Angelo Maccaro, Giulia Renisi, Giulia Viero, Harsimran Kaur, Arunaloke Chakrabarti, Andrea Gori and 2 more

Abstract readReview
In one paragraph

Review in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Mucormycosis.Infectious disease clinics of North America · 2025
    Review
  9. Article
  10. Review
  11. Article
  12. Opportunistic Fungal Infection by Mucorales in Liver Transplantation: Case Report.Transplant infectious disease : an official journal of the Transplantation Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Emanuele PalombaDepartment of Infectious Diseases, Luigi Sacco Hospital, Milan, Italy.ORCID https://orcid.org/0000-0003-1386-6180
Marta ColaneriDepartment of Infectious Diseases, Luigi Sacco Hospital, Milan, Italy.ORCID https://orcid.org/0000-0002-5939-9576
Cecilia AzzaràInfectious Diseases Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Marco FavaInfectious Diseases Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Angelo MaccaroInfectious Diseases Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Giulia RenisiInfectious Diseases Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Giulia VieroInfectious Diseases Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Harsimran KaurDepartment of Medical Microbiology, Postgraduate Institute of Medical Institution and Research, Chandigarh, India.ORCID https://orcid.org/0000-0002-4871-8113
Arunaloke ChakrabartiDepartment of Infectious Disease and Microbiology, Doodhadhari Burfani Hospital and Research Institute, Haridwar, India.ORCID https://orcid.org/0000-0003-1555-3807
Andrea GoriDepartment of Infectious Diseases, Luigi Sacco Hospital, Milan, Italy.
Andrea LombardiInfectious Diseases Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.ORCID https://orcid.org/0000-0002-0383-9579
Alessandra BanderaInfectious Diseases Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucormycosis is an emerging disease primarily affecting the immunocompromised host, but scarce evidence is available for solid organ transplant recipients (SOTRs). We systematically reviewed 183 cases occurring in SOTRs, exploring epidemiology, clinical characteristics, causative pathogens, therapeutic approaches, and outcomes. Kidney transplants accounted for half of the cases, followed by heart (18.6%), liver (16.9%), and lung (10.4%). Diagnosis showed a dichotomous distribution, with 63.7% of cases reported within 100 days of transplantation and 20.6% occurring at least 1 year after transplant. The 90-day and 1-year mortality rates were 36.3% and 63.4%, respectively. Disseminated disease had the highest mortality at both time points (75% and 93%). Treatment with >3 immunosuppressive drugs showed a significant impact on 90-day mortality (odds ratio [OR], 2.33; 95% CI, 1.02-5.66;

Indexed as

epidemiologymortalitymucormycosisorgan transplantsystematic review

Identifiers

PMID38887489
PMCPMC11181195

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.