Evidence map›Paper›PMID 38887270›Full record

ArticleFrontiers in endocrinology2024

Reduced anti-Müllerian hormone action in cumulus-oocyte complexes is beneficial for oocyte maturation without affecting oocyte competence.

Fuhua Xu, Konstantin Bagnjuk, Nuria Marti-Gutierrez, Sathya Srinivasan, Artur Mayerhofer, David Lee, Tanja Pejovic, Shoukhrat Mitalipov, Jing Xu

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Effect of Anti-Müllerian Hormone on Oocytes In Vitro Maturation in Sheep.International journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fuhua XuDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, United States.
Konstantin BagnjukBiomedical Center, Cell Biology, Anatomy III, Faculty of Medicine, Ludwig Maximilian University of Munich, Planegg-Martinsried, Germany.
Nuria Marti-GutierrezCenter for Embryonic Cell and Gene Therapy, Oregon Health & Science University, Portland, OR, United States.
Sathya SrinivasanIntegrated Pathology Core, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, United States.
Artur MayerhoferBiomedical Center, Cell Biology, Anatomy III, Faculty of Medicine, Ludwig Maximilian University of Munich, Planegg-Martinsried, Germany.
David LeeDepartment of Obstetrics and Gynecology, School of Medicine, Oregon Health & Science University, Portland, OR, United States.
Tanja PejovicObstetrics and Gynecology Health Center, Providence, Medford, OR, United States.
Shoukhrat MitalipovCenter for Embryonic Cell and Gene Therapy, Oregon Health & Science University, Portland, OR, United States.
Jing XuDepartment of Biology & Chemistry, School of Health Sciences, Liberty University, Lynchburg, VA, United States.

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
Anti-Mullerian Hormone Actions to Control Primate FolliculogenesisR01HD082208 · NICHD · OREGON HEALTH & SCIENCE UNIVERSITY · PI KRIEG, ADAM J · 2015 to 2025
$5.3M
NICHD NIH HHS R01 HD082208NIH HHS P51 OD011092
6 · The paper itself

Abstract

Anti-Müllerian hormone (AMH) is a key paracrine/autocrine factor regulating folliculogenesis in the postnatal ovary. As antral follicles mature to the preovulatory stage, AMH production tends to be limited to cumulus cells. Therefore, the present study investigated the role of cumulus cell-derived AMH in supporting maturation and competence of the enclosed oocyte. Cumulus-oocyte complexes (COCs) were isolated from antral follicles of rhesus macaque ovaries for

Indexed as

Anti-Mullerian HormoneCumulus CellsIn Vitro Oocyte Maturation TechniquesMacaca mulattaOocytesAnimalsCells, CulturedEmbryonic DevelopmentFemaleFertilization in VitroGranulosa CellsHumansMeiosisOogenesisOvarian FollicleAnti-Mullerian Hormoneanti-Müllerian hormonecumulus-oocyte complexesin vitro maturationoocyte competenceoocyte maturation

Identifiers

PMID38887270
PMCPMC11180751

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.