Evidence map›Paper›PMID 38887265›Full record

ArticleFrontiers in endocrinology2024

Lateral parabrachial nucleus astrocytes control food intake.

Devesh Mishra, Jennifer E Richard, Ivana Maric, Olesya T Shevchouk, Stina Börchers, Kim Eerola, Jean-Philippe Krieger, Karolina P Skibicka

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Cholecystokinin Induces CaThe European journal of neuroscience · 2026
    Article
  3. Astrocyte involvement in metabolic regulation and disease.Trends in endocrinology and metabolism: TEM · 2025
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Devesh MishraDepartment of Physiology/Metabolic Physiology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Jennifer E RichardDepartment of Physiology/Metabolic Physiology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Ivana MaricDepartment of Physiology/Metabolic Physiology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Olesya T ShevchoukDepartment of Physiology/Metabolic Physiology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Stina BörchersDepartment of Physiology/Metabolic Physiology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Kim EerolaDepartment of Physiology/Metabolic Physiology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Jean-Philippe KriegerDepartment of Physiology/Metabolic Physiology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.
Karolina P SkibickaDepartment of Physiology/Metabolic Physiology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.

Funding

Neuroanatomical substrates underpinning brain aromatase control of feeding behavior and metabolic homeostasisR01DK129321 · NIDDK · PENNSYLVANIA STATE UNIVERSITY, THE · PI Karolina P Skibicka · 2023 to 2026
$2.0M
NIDDK NIH HHS R01 DK129321
6 · The paper itself

Abstract

Food intake behavior is under the tight control of the central nervous system. Most studies to date focus on the contribution of neurons to this behavior. However, although previously overlooked, astrocytes have recently been implicated to play a key role in feeding control. Most of the recent literature has focused on astrocytic contribution in the hypothalamus or the dorsal vagal complex. The contribution of astrocytes located in the lateral parabrachial nucleus (lPBN) to feeding behavior control remains poorly understood. Thus, here, we first investigated whether activation of lPBN astrocytes affects feeding behavior in male and female rats using chemogenetic activation. Astrocytic activation in the lPBN led to profound anorexia in both sexes, under both

Indexed as

AstrocytesEatingParabrachial NucleusAnimalsAnorexiaFeeding BehaviorFemaleGlutamic AcidMaleRatsRats, Sprague-DawleyReceptors, N-Methyl-D-AspartateGlutamic AcidReceptors, N-Methyl-D-AspartateastrocytesghrelingliaGLP-1high-fat diethindbrainlateral parabrachial nucleusNMDA

Identifiers

PMID38887265
PMCPMC11180714

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.