Evidence map›Paper›PMID 38887225›Full record

ArticleJournal of the American College of Emergency Physicians open2024

Association between emergency department disposition and mortality in patients with COVID-19 acute respiratory distress syndrome.

Katie M Lebold, Andrew R Moore, Pablo A Sanchez, Ana E Pacheco-Navarro, Christian O'Donnell, Jonasel Roque, Caitlin Parmer, Shaun Pienkos, Joseph Levitt, William J Collins and 2 more

Abstract read
In one paragraph

Article in Journal of the American College of Emergency Physicians open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Katie M LeboldDepartment of Emergency Medicine Stanford University School of Medicine Palo Alto California USA.ORCID https://orcid.org/0000-0001-6913-3758
Andrew R MooreDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine Stanford University School of Medicine Palo Alto California USA.
Pablo A SanchezDivision of Cardiovascular Medicine, Department of Medicine Stanford University School of Medicine Palo Alto California USA.
Ana E Pacheco-NavarroDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine Stanford University School of Medicine Palo Alto California USA.
Christian O'DonnellDivision of Cardiovascular Medicine, Department of Medicine Stanford University School of Medicine Palo Alto California USA.
Jonasel RoqueDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine Stanford University School of Medicine Palo Alto California USA.
Caitlin ParmerDivison of Hospital Medicine, Department of Medicine Stanford University School of Medicine Palo Alto California USA.
Shaun PienkosDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine Stanford University School of Medicine Palo Alto California USA.
Joseph LevittDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine Stanford University School of Medicine Palo Alto California USA.
William J CollinsDivison of Hospital Medicine, Department of Medicine Stanford University School of Medicine Palo Alto California USA.
Angela J RogersDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine Stanford University School of Medicine Palo Alto California USA.
Jennifer G WilsonDepartment of Emergency Medicine Stanford University School of Medicine Palo Alto California USA.

Funding

Stanford Training Program in Lung BiologyT32HL129970 · NHLBI · STANFORD UNIVERSITY · PI CORNFIELD, DAVID N., NICOLLS, MARK ROBERT · 2016 to 2025
$3.2M
NHLBI NIH HHS T32 HL129970
6 · The paper itself

Abstract

Objectives: Patients hospitalized for COVID-19 frequently develop hypoxemia and acute respiratory distress syndrome (ARDS) after admission. In non-COVID-19 ARDS studies, admission to hospital wards with subsequent transfer to intensive care unit (ICU) is associated with worse outcomes. We hypothesized that initial admission to the ward may affect outcomes in patient with COVID-19 ARDS. Methods: This was a retrospective study of consecutive adults admitted for COVID-19 ARDS between March 2020 and March 2021 at Stanford Health Care. Mortality scores at hospital admission (Coronavirus Clinical Characterization Consortium Mortality Score [4C score]) and ICU admission (Simplified Acute Physiology Score III [SAPS-III]) were calculated, as well as ROX index for patients on high flow nasal oxygen. Patients were classified by emergency department (ED) disposition (ward-first vs. ICU-direct), and 28- and 60-day mortality and highest level of respiratory support within 1 day of ICU admission were compared. A second cohort (April 2021‒July 2022, Results: A total of 157 patients were included, 48% of whom were first admitted to the ward ( Conclusion: Despite similar baseline risk scores, ward-first patients with COVID-19 ARDS had increased mortality and escalation to mechanical ventilation compared to ICU-direct patients. Ward-first patients requiring ICU upgrade within 48 h were at highest risk, highlighting a need for improved identification of this group at ED admission.

Indexed as

acute respiratory distress syndromeCOVID‐19dispositionemergency department

Identifiers

PMID38887225
PMCPMC11180691

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.