Evidence map›Paper›PMID 38887205›Full record

ArticleCNS neuroscience & therapeutics2024

Mapping of afferent and efferent connections of phenylethanolamine N-methyltransferase-expressing neurons in the nucleus tractus solitarii.

Mengchu Zhu, Shirui Jun, Xiaojun Nie, Jinting Chen, Yinchao Hao, Hongxiao Yu, Xiang Zhang, Lu Sun, Yuelin Liu, Xiangshan Yuan and 2 more

Abstract read
In one paragraph

Article in CNS neuroscience & therapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mengchu ZhuDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, Hebei, China.
Shirui JunDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, Hebei, China.ORCID 0000-0003-1594-7590
Xiaojun NieDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, Hebei, China.
Jinting ChenDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, Hebei, China.
Yinchao HaoDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, Hebei, China.
Hongxiao YuDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, Hebei, China.
Xiang ZhangDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, Hebei, China.
Lu SunDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, Hebei, China.
Yuelin LiuDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, Hebei, China.
Xiangshan YuanDepartment of Anatomy and Histoembryology, School of Basic Medical Sciences, Fudan University, Shanghai, China.
Fang YuanDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, Hebei, China.ORCID 0000-0002-2590-1572
Sheng WangDepartment of Neurobiology, Hebei Medical University, Shijiazhuang, Hebei, China.ORCID 0000-0001-9579-4808

Funding

National Natural Science Foundation of China 31971050National Natural Science Foundation of China 31971110National Natural Science Foundation of China 32171142Natural Science Foundation of Hebei Province H2021206187Natural Science Foundation of Hebei Province for Innovative Research Group Project H2021206203Open Project of Key Laboratory of Longevity and Aging-related Diseases KLLAD202201Science Research Project of Hebei Education Department QN2022177
6 · The paper itself

Abstract

objectivePhenylethanolamine N-methyltransferase (PNMT)-expressing neurons in the nucleus tractus solitarii (NTS) contribute to the regulation of autonomic functions. However, the neural circuits linking these neurons to other brain regions remain unclear. This study aims to investigate the connectivity mechanisms of the PNMT-expressing neurons in the NTS (NTS

methodsThe methodologies employed in this study included a modified rabies virus-based retrograde neural tracing technique, conventional viral anterograde tracing, and immunohistochemical staining procedures.

resultsA total of 43 upstream nuclei projecting to NTS

conclusionOur research findings demonstrate that NTS

Indexed as

Afferent PathwaysEfferent PathwaysNeuronsPhenylethanolamine N-MethyltransferaseSolitary NucleusAnimalsBrain MappingMaleRatsRats, Sprague-DawleyPhenylethanolamine N-Methyltransferasemappingneural circuitnucleus tractus solitariiPNMT

Identifiers

PMID38887205
PMCPMC11183208

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.