Evidence map›Paper›PMID 38887094›Full record

ArticleTrends in hearing

Safety and Early Outcomes of Cochlear Implantation of Nucleus Devices in Infants: A Multi-Centre Study.

Tal Honigman, Sharon L Cushing, Blake C Papsin, Susan Waltzman, Jennifer Woodard, Sara Neumann, Matthew B Fitzgerald, Karen A Gordon

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Trends in hearing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tal HonigmanDepartment of Otolaryngology, The Hospital for Sick Children, Toronto, ON, Canada.
Sharon L CushingDepartment of Otolaryngology, The Hospital for Sick Children, Toronto, ON, Canada.
Blake C PapsinDepartment of Otolaryngology, The Hospital for Sick Children, Toronto, ON, Canada.
Susan WaltzmanDepartment of Otolaryngology-Head and Neck Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Jennifer WoodardDepartment of Otolaryngology/Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Sara NeumannHearts for Hearing, Oklahoma City, OK, USA.
Matthew B FitzgeraldDepartment of Otolaryngology-Head and Neck Surgery, Stanford University, Palo Alto, CA, USA.
Karen A GordonDepartment of Otolaryngology-Head & Neck Surgery, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-2491-3125

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This multi-center study examined the safety and effectiveness of cochlear implantation of children between 9 and 11 months of age. The intended impact was to support practice regarding candidacy assessment and prognostic counseling of pediatric cochlear implant candidates. Data in the clinical chart of children implanted at 9-11 months of age with Cochlear Ltd devices at five cochlear implant centers in the United States and Canada were included in analyses. The study included data from two cohorts implanted with one or two Nucleus devices during the periods of January 1, 2012-December 31, 2017 (Cohort 1, n = 83) or between January 1, 2018 and May 15, 2020 (Cohort 2, n = 50). Major adverse events (requiring another procedure/hospitalization) and minor adverse events (managed with medication alone or underwent an expected course of treatment that did not require surgery or hospitalization) out to 2 years post-implant were monitored and outcomes measured by audiometric thresholds and parent-reports on the IT-MAIS and LittlEARS questionnaires were collected. Results revealed 60 adverse events in 41 children and 227 ears implanted (26%) of which 14 major events occurred in 11 children; all were transitory and resolved. Improved hearing with cochlear implant use was shown in all outcome measures. Findings reveal that the procedure is safe for infants and that they show clear benefits of cochlear implantation including increased audibility and hearing development.

Indexed as

Cochlear ImplantationCochlear ImplantsAuditory ThresholdCanadaFemaleHumansInfantMalePostoperative ComplicationsRetrospective StudiesTime FactorsTreatment OutcomeUnited Statesaided audiogramchildrendeafnessearly treatmenthearing lossIT-MAIS and LittlEARS questionnaires

Identifiers

PMID38887094
PMCPMC11185016

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.