Observational studyThe Journal of international medical research2024
Comparison of staining quality between rapid and routine hematoxylin and eosin staining of frozen breast tissue sections: an observational study.
Observational study in The Journal of international medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Suspected Microplastic-like Particles in Human Gastric Autopsy Samples: An Exploratory Histopathological and Biochemical Study.Life (Basel, Switzerland) · 2026Article
- Screening for Suspected Microplastic-like Particles in Post-Mortem Human Liver: Correlating Histopathological Alterations with Clinical Profiles.Life (Basel, Switzerland) · 2026Article
- Integration of Raman Spectroscopy and Metabolomics for Early Breast Cancer Detection and Classification.Cancer medicine · 2026Article
- A novel phage encoding host defense modulators demonstrates in-vivo therapeutic efficacy against carbapenem-resistant E. coli ST1432.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Article
- Integrated Single-Cell and Bulk Transcriptomics Unveils Immune Profiles in Chick Erythroid Cells upon Avian PathogenicAnimals : an open access journal from MDPI · 2026Article
- Gut Microbiota Dysbiosis and Neuroimmune Alterations in a Postmenopausal-Stress Rat Model.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025Article
- Seq-Scope: repurposing Illumina sequencing flow cells for high-resolution spatial transcriptomics.Nature protocols · 2025Review
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Authors and funding
6 authors.
Funding
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Abstract
objectiveTo compare the staining quality between rapid hematoxylin and eosin (H&E) staining and routine H&E staining of frozen breast tissue sections.
methodsIn this cross-sectional observational study, 120 frozen breast tissue sections were randomly assigned to rapid or routine H&E staining (
resultsThe staining time for rapid staining was approximately 3 minutes, whereas that of routine staining was approximately 12 minutes. There were no significant differences in the staining quality scores or proportions of sections in each grade between the two staining methods. The proportions of sections that were classified as excellent or good were 96.7% and 98.3% for rapid and routine staining, respectively.
conclusionsIn frozen breast tissue sections, rapid H&E staining may provide staining quality that is comparable to that of routine staining, while markedly reducing the staining time.
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